The Clinical Research and Epidemiology in Diabetes and Endocrinology Training Program at Johns Hopkins University is applying for its second competitive renewal after completing 9.5 years of funding. In 2002 Drs. Christopher Saudek and Frederick Brancati established a training program at Johns Hopkins devoted to clinical and epidemiologic research in diabetes and endocrinology. Ten years later, it remains the only one of its kind in the US. Thus far, we have successfully trained 16 young scholars (6 pre-docs and 10 post docs) who have produced 61 peer-reviewed scientific papers and who hold research positions across the country. During the last funding cycle, we trained 3 under-represented minorities (2 on diversity supplements) and 12 women. Our program includes 3 pre-doctoral and 3 post-doctoral slots, all of which were filled during each of the past 5 years. Following Dr. Saudek's untimely death, Dr. Brancati assumed leadership of the training program, together with Dr. Sherita Golden, an endocrinologist cross-trained in epidemiology. This new leadership team, supported by an Executive and Advisory Committee, proposes a third cycle of funding with the following specific aims: (1) to recruit a diverse group of top-notch young trainees in endocrinology (post-docs) and epidemiology (pre-docs) from a national pool of talent attracted to Johns Hopkins;(2) to enroll them in rigorous, thesis-bearing Masters'and PhD programs in Epidemiology and Clinical Investigation in the Johns Hopkins Bloomberg School of Public Health;(3) to expose them to a strong team-oriented, multi-disciplinary clinical and epidemiologic research culture in the Welch Center for Prevention, Epidemiology, and Clinical Research-the premier educational home for clinical research training at Johns Hopkins;(4) to guide each trainee to an experienced, NIH- funded mentor who will take responsibility for the successful completion of a significant thesis project. To accomplish these goals, our program brings together faculty and trainees from the Divisions of Adult and Pediatric Endocrinology and General Internal Medicine (School of Medicine), the Department of Epidemiology (School of Public Health), the Welch Center for Prevention, Epidemiology, and Clinical Research, and the School of Nursing. Sixteen mentors will serve as primary faculty and were selected for their expertise, excellence in mentoring, and active NIH funding. New mentors have been added with expertise in clinical trials, health disparities, behavioral science, and community-based interventions. If our proposal is successful, then Johns Hopkins will continue to play a major national role in training the next generation of patient- and population-oriented researchers in diabetes and endocrinology.

Public Health Relevance

The goal of our program is to play a national role in training the next generation of patient- and population-oriented researchers in diabetes and endocrinology. We will accomplish this through enrolling talented trainees in endocrinology and epidemiology into thesis-bearing Masters'and PhD programs through our School of Public Health and exposing them to a multi-disciplinary clinical and epidemiological research culture supported by experienced, NIH-funded mentors.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
2T32DK062707-11A1
Application #
8474183
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
2002-09-30
Project End
2018-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
11
Fiscal Year
2013
Total Cost
$287,112
Indirect Cost
$15,603
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Palta, Priya; Xue, Qian-Li; Deal, Jennifer A et al. (2015) Interleukin-6 and C-Reactive Protein Levels and 9-Year Cognitive Decline in Community-Dwelling Older Women: The Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci 70:873-8
Corriere, Mark D; Yao, W; Xue, Q L et al. (2014) The association of neighborhood characteristics with obesity and metabolic conditions in older women. J Nutr Health Aging 18:792-8
Kalyani, Rita Rastogi; Corriere, Mark; Ferrucci, Luigi (2014) Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. Lancet Diabetes Endocrinol 2:819-29
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Maruthur, Nisa M; Gribble, Matthew O; Bennett, Wendy L et al. (2014) The pharmacogenetics of type 2 diabetes: a systematic review. Diabetes Care 37:876-86
Remigio-Baker, Rosemay A; Allison, Matthew A; Schreiner, Pamela J et al. (2014) Difference by sex but not by race/ethnicity in the visceral adipose tissue-depressive symptoms association: the Multi-Ethnic Study of Atherosclerosis. Psychoneuroendocrinology 47:78-87
Gribble, Matthew O; Around Him, Deana M (2014) Ethics and Community Involvement in Syntheses Concerning American Indian, Alaska Native, or Native Hawaiian Health: A Systematic Review. AJOB Empir Bioeth 5:1-24
Palta, Priya; Samuel, Laura J; Miller 3rd, Edgar R et al. (2014) Depression and oxidative stress: results from a meta-analysis of observational studies. Psychosom Med 76:12-9
Gribble, Matthew O; Tang, Wan-Yee; Shang, Yan et al. (2014) Differential methylation of the arsenic (III) methyltransferase promoter according to arsenic exposure. Arch Toxicol 88:275-82
Palta, Priya; Golden, Sherita H; Teresi, Jeanne et al. (2014) Mild cognitive dysfunction does not affect diabetes mellitus control in minority elderly adults. J Am Geriatr Soc 62:2363-8

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