The Pediatric Endocrinology Research Training Program at the University of Chicago will train pediatric physician-scientists in the investigation of endocrine diseases.This training program will help fill the national shortage of physician-scientists in the area of pediatric endocrinology. Four research training slots are requested so that two trainees can be entered annually into a two-year research training program. Thus, this program is for trainees who have had introductory laboratory and course work in their initial year of pediatric endocrinology training and have developed a research project to which they are prepared to dedicate 80% effort for the two-year training period. The training is based in a newly combined Pediatric-Adult Endocrinology, Diabetes, and Metabolism unit, the Institute for Endocrine Discovery and Clinical Care. The Senior Training Faculty numbers 15 investigators from four University departments (Medicine, Pediatrics, Human Genetics, Health Studies) who carry out a broad range of endocrine-related clinical and basic research supported by a substantial base of NIH and other peer-reviewed research grants. Each is an established investigator. In addition, the program is aided by the participation of 13 Associate Training Faculty from the Departments of Medicine, Pediatrics, Ob/Gyn and Health Studies. The University provides a rich environment of other faculty and physical resources. Trainees are selected on the basis of prior individual accomplishments including prior research training and experience as well as commitment to an academic research career. Trainees select a basic and clinical research mentor and an advisor, and the trainee and mentors jointly identify a primary and secondary research project. Trainees then undergo at least 2 years of training in the research laboratory of the preceptor(s), during which time they assume a progressively greater responsibility for developing research hypotheses, designing experiments, analyzing the data and preparing abstracts and scientific manuscripts. In the final year of training, an area of research is identified which is sufficiently different from the research of the preceptor to allow the trainee to submit a peer-reviewed mentored research grant proposal. This research training occurs within the framework of a required core curriculum consisting of courses that describe and review current research methodology and research advances as well as statistical analysis of research data. The setting is one that emphasizes translational research and timely monitoring of trainee progress.

Public Health Relevance

The Pediatric Endocrinology Research Training Program at the University of Chicago aims to produce highly qualified physician-scientists trained in the use of a variety of modern experimental techniques that will enable them to translate fundamental discoveries into improved medical care of diabetes and other endocrine disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK064582-09
Application #
8287688
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
2003-07-01
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
9
Fiscal Year
2012
Total Cost
$86,606
Indirect Cost
$8,929
Name
University of Chicago
Department
Pediatrics
Type
Schools of Medicine
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Sobotka, Sarah A; Danielson, Kirstie K; Drum, Melinda L et al. (2014) Maternal body mass index (BMI) is independently associated with the control of diabetes mellitus in young patients. Pediatr Nurs 40:187-94
Rosenfield, Robert L; Bordini, Brian; Yu, Christine (2013) Comparison of detection of normal puberty in girls by a hormonal sleep test and a gonadotropin-releasing hormone agonist test. J Clin Endocrinol Metab 98:1591-601
Greeley, Siri Atma W; Tucker, Susan E; Naylor, Rochelle N et al. (2010) Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab 21:464-72
Rosenfield, Robert L; Bordini, Brian (2010) Evidence that obesity and androgens have independent and opposing effects on gonadotropin production from puberty to maturity. Brain Res 1364:186-97
Zimmer, Carrie A; Ehrmann, David A; Rosenfield, Robert L (2010) Potential diagnostic utility of intermittent administration of short-acting gonadotropin-releasing hormone agonist in gonadotropin deficiency. Fertil Steril 94:2697-702
Bordini, Brian; Littlejohn, Elizabeth; Rosenfield, Robert L (2009) Blunted sleep-related luteinizing hormone rise in healthy premenarcheal pubertal girls with elevated body mass index. J Clin Endocrinol Metab 94:1168-75