Abstract

The Regenerative Medicine training program is supported by a T32 Training Grant from NIDDK. This renewal proposal requests 4 pre-doctoral and 2 post-doctoral positions. In addition, the Regeneration Project of the McKnight Brain Institute provides an additional 2 post-doctoral fellowships that require an inter-institutional collaboration for the mentoring. Specific training is provided by the Stem cell biology/Regenerative medicine course offered through the IDP. The course consists of three modules 1) Basic stem cell biology. 2) Translational stem cell biology. 3) Clinical cell based therapies. In addition T32 trainees help organize and run the annual Regeneration Project Scientific Meeting that brings in invited speakers from around the world to discuss recent advances in Regenerative Medicine. The trainees are also required to present their work at this forum.

Public Health Relevance

The Regenerative Medicine training program supports both pre-doctoral and post-doctoral fellows. The fellows are trained to translate basic science findings in stem cell biology into novel regenerative therapies for a wide range of human diseases. This emerging field has the potential to make the promise of 'Personalized' medicine a reality.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
4T32DK074367-10
Application #
9084541
Study Section
Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
Program Officer
Bishop, Terry Rogers
Project Start
2006-07-01
Project End
2017-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
10
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Genetics
Type
Schools of Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Hamazaki, Takashi; El Rouby, Nihal; Fredette, Natalie C et al. (2017) Concise Review: Induced Pluripotent Stem Cell Research in the Era of Precision Medicine. Stem Cells 35:545-550
Gilkes, J A; Bloom, M D; Heldermon, C D (2016) Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10. Gene Ther 23:263-71
Pi, Liya; Jorgensen, Marda; Oh, Seh-Hoon et al. (2015) A disintegrin and metalloprotease with thrombospondin type I motif 7: a new protease for connective tissue growth factor in hepatic progenitor/oval cell niche. Am J Pathol 185:1552-63
Pi, Liya; Robinson, Paulette M; Jorgensen, Marda et al. (2015) Connective tissue growth factor and integrin ?v?6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice. Hepatology 61:678-91
Cheng, Xiaodong; Byrne, Michael; Brown, Kevin D et al. (2015) PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice. Blood 126:1585-94
Lopez, David; Scott, Edward W (2015) Generation of axolotl hematopoietic chimeras. J Biol Methods 2:
Maden, Malcolm; Avila, Daima; Roy, Molly et al. (2015) Tissue specific reactions to positional discontinuities in the regenerating axolotl limb. Regeneration (Oxf) 2:137-147
Lopez, David; Lin, Li; Monaghan, James R et al. (2014) Mapping hematopoiesis in a fully regenerative vertebrate: the axolotl. Blood 124:1232-41
Cogle, Christopher R; Goldman, Devorah C; Madlambayan, Gerard J et al. (2014) Functional integration of acute myeloid leukemia into the vascular niche. Leukemia 28:1978-1987
Silver, Daniel J; Siebzehnrubl, Florian A; Schildts, Michela J et al. (2013) Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment. J Neurosci 33:15603-17

Showing the most recent 10 out of 21 publications