Diabetes mellitus and obesity are important causes of morbidity and mortality in the United States and other industrialized and developing nations. The University of Illinois at Chicago is committed to training new investigators to address this major health care problem. This training program will target physicians who are committed to pursuing a career in investigative medicine related to diabetes, nutrition and obesity research. Trainees will complete 3 years of intensively mentored research training in an environment that fosters interaction between clinical and basic sciences, and encourages translational research. The typical trainee will complete 1 year of clinical training in Endocrinology, Diabetes and Metabolism (instead of 2) before entering this program. Reducing the time required for clinical training in Endocrinology (and in Internal Medicine for those in the Physician-Investigator Pathway) will enhance recruitment and retention of candidates targeting a career in investigative medicine. Outstanding candidates from other clinical disciplines also can be considered for research training. By design, we provide excellent opportunities for focused mentored training in laboratory-based and clinical research, behavioral and preventive medicine, and community-based research related to diabetes and obesity. Candidates will complete selected graduate level courses pertinent to their mentored research program, and they will receive training in research integrity and ethics. Mentors are selected based on areas of expertise and interests, complementary research skills, achievement in extramural funding, scientific productivity, and record of strong mentorship. Trainees will develop individualized research programs, learn to write grant proposals, and receive career counseling and assistance in academic job placement. The success of the program will be evaluated based on the academic success of trainees, and progress will be closely monitored by a research advisory committee, internal executive committee, external advisory board and the principle investigator. This program is designed to provide excellent training for physician investigators in research related to diabetes and obesity in a vibrant and scientifically responsible environment that has a strong commitment to attracting individuals from under-represented minorities.

Public Health Relevance

Diabetes mellitus and obesity are major causes of morbidity and mortality in this country and around the world. This training program will provide in-depth training in basic, clinical and community-based research to future Physician-Investigators targeting this area of critical need.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK080674-05
Application #
8728816
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
$187,296
Indirect Cost
$14,728
Name
University of Illinois at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Syed, Samina T; Sharp, Lisa K; Kim, Yoonsang et al. (2016) Relationship Between Medication Adherence and Distance to Dispensing Pharmacies and Prescribers Among an Urban Medicaid Population with Diabetes Mellitus. Pharmacotherapy 36:590-7
Barnosky, Adrienne R; Hoddy, Kristin K; Unterman, Terry G et al. (2014) Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings. Transl Res 164:302-11
York, Jason M; Castellanos, Karla J; Cabay, Robert J et al. (2014) Inhibition of the nucleotide-binding domain, leucine-rich containing family, pyrin-domain containing 3 inflammasome reduces the severity of experimentally induced acute pancreatitis in obese mice. Transl Res 164:259-69
Manickam, Buvana; Neagu, Valeriu; Kukreja, Subhash C et al. (2013) Relationship between glycated hemoglobin and circulating 25-hydroxyvitamin D concentration in African American and Caucasian American men. Endocr Pract 19:73-80
Akasheh, Rand T; Pang, Jingbo; York, Jason M et al. (2013) New pathways to control inflammatory responses in adipose tissue. Curr Opin Pharmacol 13:613-7
Huang, Zhi Hua; Manickam, Buvana; Ryvkin, Victoria et al. (2013) PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity. J Clin Endocrinol Metab 98:E17-24
Syed, Samina T; Gerber, Ben S; Sharp, Lisa K (2013) Traveling towards disease: transportation barriers to health care access. J Community Health 38:976-93
Manickam, Buvana; Washington, Terri; Villagrana, Nancy E et al. (2012) Determinants of circulating 25-hydroxyvitamin D and bone mineral density in young physicians. Endocr Pract 18:219-26