Training in epidemiology and outcomes research is essential to prepare the next generation of researchers in a rapidly moving field. Discoveries in genetics, pathophysiology, diagnosis, and treatment of several Gl and liver disorders have been made at a very rapid pace over the past few years. Modern clinical and translational researchers need to be equipped with extensive training in the methods and conduct of research in areas that are becoming highly sophisticated and specialized;these include conventional epidemiology, clinical epidemiology and outcomes, genetic and molecular epidemiology, and health services research. These areas address the need for translational research both from bench to bedside as well as from bedside to clinical practice. The proposed training program has three objectives: (1) To produce physician scientists who are thoroughly trained in the content areas, methods, and ethics critical for epidemiology and outcomes research in gastroenterology and hepatology; (2) To produce physician scientists who have mastered basic research skills, including project design, planning, funding, execution, management, and reporting;and (3) To produce physician scientists who will pursue a research agenda that will new discoveries as well as make the best use of current discoveries to make the health care safer, more effective, more patient-centered, more timely, more efficient, and more equitable. The program will take advantage of outstanding expertise in research and mentoring in epidemiology and outcomes research available at Baylor College of Medicine and UT-School of Public Health including the Gl and Liver Section and the Houston Center for Quality of Care and Utilization Studies (HCQCUS). The proposed fellowship training program has four elements: 1) vigorous mentoring for each individual fellow in a self-selected area of concentration to engender the development of a feasible career research agenda that has potential for substantial impact, and 2) formal research training resulting in a master's degree to provide a foundation of research skills, 3) Applied research seminars to model use of research skills and provide a foundation in health services research knowledge and skills, and 4) participation in the research process as a co- investigator and as a principle investigator to provoke application of research skills.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
3T32DK083266-04S1
Application #
8666130
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
2010-04-01
Project End
2015-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
4
Fiscal Year
2013
Total Cost
$29,411
Indirect Cost
$2,179
Name
Baylor College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Fischbach, Lori A; Graham, David Y; Kramer, Jennifer R et al. (2014) Association between Helicobacter pylori and Barrett's esophagus: a case-control study. Am J Gastroenterol 109:357-68
Kruse, Robert L; Kramer, Jennifer R; Tyson, Gia L et al. (2014) Clinical outcomes of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients. Hepatology 60:1871-8
Kramer, Jennifer R; Shakhatreh, Mohammad H; Naik, Aanand D et al. (2014) Use and yield of endoscopy in patients with uncomplicated gastroesophageal reflux disorder. JAMA Intern Med 174:462-5
Thrift, Aaron P; Garcia, Jose M; El-Serag, Hashem B (2014) A multibiomarker risk score helps predict risk for Barrett's esophagus. Clin Gastroenterol Hepatol 12:1267-71
Singh, Siddharth; Garg, Sushil Kumar; Singh, Preet Paul et al. (2014) Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with Barrett's oesophagus: a systematic review and meta-analysis. Gut 63:1229-37
Khandwalla, Hashim E; Graham, David Y; Kramer, Jennifer R et al. (2014) Barrett's esophagus suspected at endoscopy but no specialized intestinal metaplasia on biopsy, what's next? Am J Gastroenterol 109:178-82
El-Serag, Hashem B; Sweet, Stephen; Winchester, Christopher C et al. (2014) Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 63:871-80
Kanwal, Fasiha; White, Donna L; Tavakoli-Tabasi, Shahriar et al. (2014) Many patients with interleukin 28B genotypes associated with response to therapy are ineligible for treatment because of comorbidities. Clin Gastroenterol Hepatol 12:327-333.e1
Tyson, Gia L; Kramer, Jennifer R; Duan, Zhigang et al. (2013) Prevalence and predictors of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients. Hepatology 58:538-45
Tyson, Gia L; Richardson, Peter A; White, Donna L et al. (2013) Dietary fructose intake and severity of liver disease in hepatitis C virus-infected patients. J Clin Gastroenterol 47:545-52

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