Continuation of a multidisciplinary predoctoral training program in biomedical imaging and spectroscopy (BMIS) is proposed. The BMIS program provides a unique educational experience based on fundamental training in the mathematical and engineering principles of image science combined with a focus on and exposure to a broad range of biological applications. This program draws on the strength of the faculty and research programs in biomedical imaging and spectroscopy at the University of Arizona. Areas of emphasis include magnetic resonance imaging, magnetic resonance spectroscopy, gamma-ray imaging, X-ray imaging, ultrasound imaging, optical imaging, optical spectroscopy, image processing, and image quality assessment, which are often tied to specific scientific investigation across a wide spectrum of applications. A specialized curriculum is defined for BMIS students during the first two years, which involves courses in applied physiology, biology, the mathematical principles of image science, as well as the physics and engineering principles at the foundation of modem imaging and spectroscopic systems. These courses provide students with the knowledge base necessary to carry out advanced research on the development and utilization of advanced biomedical imaging and spectroscopic technologies. In addition to the course work, students enrolled in the program are required to complete semester-long rotations (typically three) in different research laboratories prior to selecting a laboratory and mentor for their Ph.D. dissertation work. These rotations provide students with exposure to multiple disciplines and research environments and help create and foster increased collaboration among researchers at the University of Arizona. Identity and connection to the training program are fostered through regular meetings, seminars, and community activities. Students are recruited into BMIS through existing graduate programs at the University of Arizona. The primary conduits for recruiting students are through the graduate programs in Optical Sciences, Biomedical Engineering, and Physiological Sciences. Outstanding students from other programs, such as Applied Math, Electrical and Computer Engineering, Physics, and Cancer Biology, are encouraged and eligible to apply. Program funds are used to fully support students during their first two years after which time they are supported in the research laboratory of their primary mentor.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZEB1-OSR-B (J1))
Program Officer
Baird, Richard A
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Arizona
Schools of Medicine
United States
Zip Code
Keenan, Molly; Tate, Tyler H; Kieu, Khanh et al. (2017) Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection. Biomed Opt Express 8:124-136
Risi, Matthew D; Rouse, Andrew R; Chambers, Setsuko K et al. (2016) Pilot Clinical Evaluation of a Confocal Microlaparoscope for Ovarian Cancer Detection. Int J Gynecol Cancer 26:248-54
Brand, Jonathan F; Furenlid, Lars R; Altbach, Maria I et al. (2016) Task-based optimization of flip angle for fibrosis detection in T1-weighted MRI of liver. J Med Imaging (Bellingham) 3:035502
Tate, Tyler H; Baggett, Brenda; Rice, Photini F S et al. (2016) Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection. J Biomed Opt 21:56005
Mu, Tingkui; Chen, Zeyu; Pacheco, Shaun et al. (2016) Generation of a controllable multifocal array from a modulated azimuthally polarized beam. Opt Lett 41:261-4
Pacheco, Shaun; Milster, Tom; Liang, Rongguang (2015) Analysis of grating doublets for achromatic beam-splitting. Opt Express 23:22939-52
Pacheco, Shaun; Brand, Jonathan F; Zaverton, Melissa et al. (2015) Sensitivity analysis and optimization method for the fabrication of one-dimensional beam-splitting phase gratings. Opt Express 23:11771-82
Risi, Matthew D; Makhlouf, Houssine; Rouse, Andrew R et al. (2015) Analysis of multimode fiber bundles for endoscopic spectral-domain optical coherence tomography. Appl Opt 54:101-13
Hagio, Tomoe; Huang, Chuan; Abidov, Aiden et al. (2015) T2 mapping of the heart with a double-inversion radial fast spin-echo method with indirect echo compensation. J Cardiovasc Magn Reson 17:24
Rosado-Toro, José A; Barr, Tomoe; Galons, Jean-Philippe et al. (2015) Automated breast segmentation of fat and water MR images using dynamic programming. Acad Radiol 22:139-48

Showing the most recent 10 out of 26 publications