The Department of Radiology at the University of Pennsylvania proposes continuation of an innovative training program with the aim of developing imaging clinician scientists. The expanding role of imaging in clinical care and biomedical research has resulted in an acute need for imaging based clinician scientists. There is a talented pool of resident applicants to academic radiology residency programs across the US, with only a small fraction persuing academic careers. Even a smaller fraction of trainees are developed into clinician scientists. The training program described in this proposal, builds on the excellent clinical training programs and the large research infrastructure with Penn's Radiology department in order to develop a residency track designed for trainees interested in careers as imaging scientists. The research track includes 1 year of research training during residency and a second optional research fellowship year. Chnical training will focus on areas of specific interest to the trainee in addition to meeting the requirement for board certification. In addition to the research perceptorships, the program includes didactic courses in imaging technology, basic biology, biostastistics and clinical research design. Research seminars and close mentoring also represent significant components of the program. Experience in the first cycle ofthis training program suggests that an integrated training program offered through the National Residents Matching program will offer an opportunity to engage residents early in their training resulting in committed, well-trained imaging clinical scientists, meeting a national need.

Public Health Relevance

This program represents an integrated training program to develop clinician scientists in the domain of imaging in the context of a Radiology residency. Imaging clinician scientists are needed to develop and implement new medical imaging methods that will advance our ability to diagnose and monitor disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
5T32EB004311-09
Application #
8490717
Study Section
Special Emphasis Panel (ZEB1-OSR-C (J1))
Program Officer
Baird, Richard A
Project Start
2005-05-01
Project End
2015-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
9
Fiscal Year
2013
Total Cost
$118,052
Indirect Cost
$14,352
Name
University of Pennsylvania
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Zhou, Rong; Pantel, Austin R; Li, Shihong et al. (2017) [18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition. Cancer Res 77:1476-1484
Pantel, Austin R; Mankoff, David A (2017) Molecular imaging to guide systemic cancer therapy: Illustrative examples of PET imaging cancer biomarkers. Cancer Lett 387:25-31
Derakhshan, Jamal J; McDonald, Elizabeth S; Siegelman, Evan S et al. (2017) Characterizing and eliminating errors in enhancement and subtraction artifacts in dynamic contrast-enhanced breast MRI: Chemical shift artifact of the third kind. Magn Reson Med :
Sellmyer, Mark A; Lee, Iljung; Hou, Catherine et al. (2017) Quantitative PET Reporter Gene Imaging with [11C]Trimethoprim. Mol Ther 25:120-126
Mankoff, David A; Edmonds, Christine E; Farwell, Michael D et al. (2016) Development of Companion Diagnostics. Semin Nucl Med 46:47-56
Schmitt, J Eric; Yi, James; Calkins, Monica E et al. (2016) Disrupted anatomic networks in the 22q11.2 deletion syndrome. Neuroimage Clin 12:420-8
Weber, Charles N; Lev-Toaff, Anna S; Levine, Marc S et al. (2016) Impact of hysterectomy on three-dimensional rectosigmoid morphology and endoscopy performance: a pilot study. Abdom Radiol (NY) 41:311-6
Edmonds, Christine E; Makvandi, Mehran; Lieberman, Brian P et al. (2016) [(18)F]FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer. Am J Nucl Med Mol Imaging 6:94-101
Madoff, David C; Gaba, Ron C; Weber, Charles N et al. (2016) Portal Venous Interventions: State of the Art. Radiology 278:333-53
Schmitt, J Eric; Scanlon, Mary H; Servaes, Sabah et al. (2015) Milestones on a Shoestring: A Cost-Effective, Semi-automated Implementation of the New ACGME Requirements for Radiology. Acad Radiol 22:1287-93

Showing the most recent 10 out of 19 publications