The UC San Diego Department of Radiology is resubmitting a competitive renewal of its postdoctoral training grant for medical residents, "Training Clinical Scientists in Radiological Imaging". Following its first five-year funding cycle the department's innovative training program has met with great success. The group of trainees has begun joining academic departments to embark on their own academic careers, with excellent publication records in high impact journals, awards for their work-one for being the most cited article in Neuroimage in 2011-and having already been awarded grants to support their work and 2 NIH R01 grants to support mentor. The growing role of imaging in clinical care and biomedical research has resulted in an acute need for clinician- scientists skilled in cutting-edge imaging science. At present, there exists a talented pool of medical student applicants to academic radiology residency programs across the U.S.A. with >20 MD/PhDs and a >50 MDs that have spent >1 year of dedicate research time during medical school per year. Only a small fraction is enticed to stay in academic radiology and pursue research. The training program described in this proposal builds on the department's proven 4-year clinical training program by adding a full research year at the beginning of residency that is then built upon throughout the clinical training by spending 6 weeks of dedicated research time per year for the balance of the 4 years. Three one-year slots will be made available to applicants to the department's five-year radiology residency program. The goal is to tailor the training program to the individual needs of each applicant and to maximize trainees'research experience at UCSD. Clinical training will focus on areas of specific interest to the trainee in addition to meeting requirements for board certification. The clinical years will be consecutive to maximize trainees'learning;however, trainees will maintain contact with their research mentors throughout their stay at UCSD. The mentorship provided by each laboratory leader during trainees'research year and by the clinical scientist throughout the five-year residency will link their research and clinical experiences and provide them a model for future careers as clinical scientists. In addition to research opportunities and career mentorship, the program includes specialized lectures tailored to the needs of each trainee and workshop specific to academic radiologists. A Match Program-offered integrated training program focusing on the career of clinical scientists ensures equal access to all applicants and allows us to engage residents early in their training, resulting in committed, well-trained clinical scientists. UCSD is well suited to train the next generation of imaging scientists. For this proposal, we have assembled 16 Radiology and 8 non-radiology mentors that together have trained over 300 trainees in the past 10 years, have over 110 active grants and $70M in grant support and their trainees have published nearly 700 papers most of which is in high impact journals.

Public Health Relevance

The UC San Diego Department of Radiology is resubmitting a competitive renewal of its postdoctoral training program that focuses on developing clinician-scientists in radiology. The trainees will be supported by 16 Radiology and 8 non-radiology mentors that together have trained over 300 trainees in the past 10 years, have over 110 active grants and $70M in grant support.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
2T32EB005970-06A1
Application #
8475253
Study Section
Special Emphasis Panel (ZEB1-OSR-D (J1))
Program Officer
Baird, Richard A
Project Start
2006-04-01
Project End
2018-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
6
Fiscal Year
2013
Total Cost
$181,472
Indirect Cost
$13,442
Name
University of California San Diego
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sheth, Vipul; Shao, Hongda; Chen, Jun et al. (2016) Magnetic resonance imaging of myelin using ultrashort Echo time (UTE) pulse sequences: Phantom, specimen, volunteer and multiple sclerosis patient studies. Neuroimage 136:37-44
Schork, Andrew J; Wang, Yunpeng; Thompson, Wesley K et al. (2016) New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology. Curr Opin Neurobiol 36:89-98
Hope, Tuva R; White, Nathan S; Kuperman, Joshua et al. (2016) Demonstration of Non-Gaussian Restricted Diffusion in Tumor Cells Using Diffusion Time-Dependent Diffusion-Weighted Magnetic Resonance Imaging Contrast. Front Oncol 6:179
Wang, Yunpeng; Bos, Steffan D; Harbo, Hanne F et al. (2016) Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Mult Scler 22:1783-1793
Yamin, Ghiam; Schenker-Ahmed, Natalie M; Shabaik, Ahmed et al. (2016) Voxel Level Radiologic-Pathologic Validation of Restriction Spectrum Imaging Cellularity Index with Gleason Grade in Prostate Cancer. Clin Cancer Res 22:2668-74
Desikan, R S; Schork, A J; Wang, Y et al. (2015) Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry 20:1588-95
Rakow-Penner, Rebecca A; White, Nathan S; Margolis, Daniel J A et al. (2015) Prostate diffusion imaging with distortion correction. Magn Reson Imaging 33:1178-81
Malone, Christopher D; Olson, Emilia S; Mattrey, Robert F et al. (2015) Tumor Detection at 3 Tesla with an Activatable Cell Penetrating Peptide Dendrimer (ACPPD-Gd), a T1 Magnetic Resonance (MR) Molecular Imaging Agent. PLoS One 10:e0137104
Reppe, Sjur; Wang, Yunpeng; Thompson, Wesley K et al. (2015) Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci. PLoS One 10:e0144531
Desikan, Rahul S; Schork, Andrew J; Wang, Yunpeng et al. (2015) Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation 131:2061-9

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