The field of Biomaterials significantly impacts the quality of life of thousands of people. Biomaterials have traditionally been used in medical devices such as hip implants, vascular grafts, and stents with new evolving applications in scaffolds/drug delivery devices for tissue engineering and regenerative medicine. However, significant challenges remain with the ability of Biomaterials to integrate seamlessly with the body, to respond and remodel with time in vivo. The full potential of Biomaterials has not yet been realized, in part, because most materials that are used today are by-products of other processes, not rationally designed with the specific medical requirements in mind. Biomedical engineering as a discipline offers a unique opportunity to address this shortcoming. Georgia Institute of Technology has had an excellent, interdisciplinary graduate program in Bioengineering for 15 years with a high quality of pre-doctoral students. The goal of GTBioMAT (Graduate Training for Rationally Designed, Integrative Biomaterials) is to leverage the existing inter-departmental and inter-university ties and provide a structured, focused, integrative training for the rational design and application of the next generation of biomimetic, integrative materials. The GTBioMAT training program will focus on integrating four important skill sets that are critical to training the future leaders in Biomaterials science and engineering: 1) the ability to elucidate Biomaterials design criteria through strong clinical interactions;2) the ability to synthesize and characterize new materials whose design is driven by an understanding of the underlying clinical and basic science issues;3) the ability to functionalize and apply these materials such that they integrate appropriately into living systems;and 4) develop leadership skills in the trainees such that they lead the next generation of Biomaterials Science and Engineering research through their innovation and research. The GTBioMAT training program proposes to introduce novel problem based learning approaches that promote self-directed inquiry and collaborative problem solving of complex but authentic biomaterials related problems. It leverages the strong research strength of the faculty at Georgia Institute of Technology and Emory University and will significantly impact the training of the future leaders in Biomaterials.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
5T32EB006343-05
Application #
8287009
Study Section
Special Emphasis Panel (ZEB1-OSR-E (M1))
Program Officer
Baird, Richard A
Project Start
2008-07-01
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2014-06-30
Support Year
5
Fiscal Year
2012
Total Cost
$173,343
Indirect Cost
$8,714
Name
Georgia Institute of Technology
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
097394084
City
Atlanta
State
GA
Country
United States
Zip Code
30332
Liu, Allen L; García, Andrés J (2016) Methods for Generating Hydrogel Particles for Protein Delivery. Ann Biomed Eng 44:1946-58
Alonas, Eric; Vanover, Daryll; Blanchard, Emmeline et al. (2016) Imaging viral RNA using multiply labeled tetravalent RNA imaging probes in live cells. Methods 98:91-8
Krishnan, Laxminarayanan; Priddy, Lauren B; Esancy, Camden et al. (2016) Delivery vehicle effects on bone regeneration and heterotopic ossification induced by high dose BMP-2. Acta Biomater :
Santangelo, Philip J; Rogers, Kenneth A; Zurla, Chiara et al. (2015) Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques. Nat Methods 12:427-32
Gutowski, Stacie M; Shoemaker, James T; Templeman, Kellie L et al. (2015) Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes. Biomaterials 44:55-70
Watstein, Daniel M; McNerney, Monica P; Styczynski, Mark P (2015) Precise metabolic engineering of carotenoid biosynthesis in Escherichia coli towards a low-cost biosensor. Metab Eng 31:171-80
Allen, Ashley B; Priddy, Lauren B; Li, Mon-Tzu A et al. (2015) Functional augmentation of naturally-derived materials for tissue regeneration. Ann Biomed Eng 43:555-67
Srinivasan, Akhil; Tahilramani, Mayank; Bentley, John T et al. (2015) Microchannel-based regenerative scaffold for chronic peripheral nerve interfacing in amputees. Biomaterials 41:151-65
McNerney, Monica P; Watstein, Daniel M; Styczynski, Mark P (2015) Precision metabolic engineering: The design of responsive, selective, and controllable metabolic systems. Metab Eng 31:123-31
Tapp, Maeling; Sullivan, Rick; Dennis, Patrick et al. (2015) Spectroscopic studies of nucleic acid additions during seed-mediated growth of gold nanoparticles. J Mater Res 30:666-676

Showing the most recent 10 out of 20 publications