Biomaterials significantly impact the quality of life of thousands of people as evident from their role in contact lenses to deep brain stimulators. In this competitive renewal application, we propose the continuation of a program that is anchored by excellent training faculty, outstanding, productive students, and a collaborative and nurturing environment. Over the past five years, the GTBioMAT training program has focused on integrating three important skill sets that are critical to training the future leaders in Biomaterals science and engineering: 1) the ability to synthesize and characterize new materials whose design is driven by an understanding of the underlying clinical and basic science issues;2) the ability to functionalize and apply these materials such that they integrate appropriately into livig systems;and 3) develop leadership skills in the trainees such that they lead the next generation of Biomaterials Science and Engineering research through their innovation and research. We have attracted a strong and diverse set of trainees to the program who are making excellent progress as evident from their publications, presentations and the leadership roles they are assuming on campus. The critical strengths of our training program are: 1) An superlative group of training faculty, with an excellent diversity by research interest, expertise, age, rank, gender and race that spans multiple departments at Georgia Tech and Emory;2) An outstanding and diverse student pool interested in Biomaterials research drawn from the best institutions across the United States;3) A unique core course sequence designed to provide contextually-relevant, skills for the rational design and synthesis of polymeric materials;4) Integration of clinical faclty at multiple levels of student training (from thesis committees to mentor luncheons);5) A unique, innovative and successful graduate leadership program for trainees whose impact extends to the campus more broadly. We believe that our training program is on target to leverage the unique strengths and environment extant at Georgia Tech and Emory School of Medicine to train the next generation of Biomaterials scientists who lead and contribute with unique skills that range from synthesizing new materials to being self-aware and influencing the world in a positive manner.

Public Health Relevance

Biomaterials affect our health in a significant way from their use as contact lenses to deep brain stimulators. As the future of medicine evolves, it is critical o design and fabricate the next generation of Biomaterials that grow and adapt with our body, deliver complex medicines and are engineered to be safe. The GTBioMAT training grant's goal is to train the next generation of scientists who will lead the charge to realizing the full potental of Biomaterials by designing and synthesizing materials based on unmet clinical needs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
2T32EB006343-06A1
Application #
8667058
Study Section
Special Emphasis Panel (ZEB1)
Program Officer
Baird, Richard A
Project Start
2006-07-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Georgia Institute of Technology
Department
Engineering (All Types)
Type
Biomed Engr/Col Engr/Engr Sta
DUNS #
City
Atlanta
State
GA
Country
United States
Zip Code
30332
Liu, Allen L; García, Andrés J (2016) Methods for Generating Hydrogel Particles for Protein Delivery. Ann Biomed Eng 44:1946-58
Alonas, Eric; Vanover, Daryll; Blanchard, Emmeline et al. (2016) Imaging viral RNA using multiply labeled tetravalent RNA imaging probes in live cells. Methods 98:91-8
Krishnan, Laxminarayanan; Priddy, Lauren B; Esancy, Camden et al. (2016) Delivery vehicle effects on bone regeneration and heterotopic ossification induced by high dose BMP-2. Acta Biomater :
Santangelo, Philip J; Rogers, Kenneth A; Zurla, Chiara et al. (2015) Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques. Nat Methods 12:427-32
Gutowski, Stacie M; Shoemaker, James T; Templeman, Kellie L et al. (2015) Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes. Biomaterials 44:55-70
Watstein, Daniel M; McNerney, Monica P; Styczynski, Mark P (2015) Precise metabolic engineering of carotenoid biosynthesis in Escherichia coli towards a low-cost biosensor. Metab Eng 31:171-80
Allen, Ashley B; Priddy, Lauren B; Li, Mon-Tzu A et al. (2015) Functional augmentation of naturally-derived materials for tissue regeneration. Ann Biomed Eng 43:555-67
Srinivasan, Akhil; Tahilramani, Mayank; Bentley, John T et al. (2015) Microchannel-based regenerative scaffold for chronic peripheral nerve interfacing in amputees. Biomaterials 41:151-65
McNerney, Monica P; Watstein, Daniel M; Styczynski, Mark P (2015) Precision metabolic engineering: The design of responsive, selective, and controllable metabolic systems. Metab Eng 31:123-31
Tapp, Maeling; Sullivan, Rick; Dennis, Patrick et al. (2015) Spectroscopic studies of nucleic acid additions during seed-mediated growth of gold nanoparticles. J Mater Res 30:666-676

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