The goal of this training program is to seek continued support of a relatively new Interdisciplinary Graduate Education in Movement and Rehabilitation Sciences (IGE-MRS) program, created at Northwestern University between the departments of Biomedical, Mechanical and Electrical Engineering and Computer Science and the departments of Physical Therapy and Human Movement Sciences, Physical Medicine & Rehabilitation, Physiology and Medicine. The mission of the IGE-MRS program is to expose engineering students to a graduate education that combines engineering, neurobiology and physical therapy and human movement sciences course work along with the associated research experiences through a DPT (Doctor in Physical Therapy) - PhD (Engineering) dual degree. The IGE-MRS program is the first program of its kind in the US to combine solid training in fundamental neurobiology and clinical physical therapy with a solid education in various engineering disciplines. This interdisciplinary training allows for the development of the scientific basis required for understanding the pathophysiological mechanisms underlying movement disorders and for designing effective rehabilitation interventions and devices. The program is comprised of mentoring engineers, neuroscientists and clinicians, and contains a broad range of expertise relevant to movement and rehabilitation science and physical therapy. The training faculty has research interests that fall loosely into three main areas: Neurobiology of movement behavior and disorders, Rehabilitation device and interface development, and Musculoskeletal Pathophysiology and Modeling. Northwestern University has a long and recognized history in the study of motor control, motor disability and recovery, and neural reorganization. Extensive research is performed in these areas at various levels, from basic animal and human studies, focused on the control of movement and movement disorders, to the development of novel rehabilitation interventions and devices that address movement disorders. This provides a robust translational environment for our IGE-MRS trainees. In this renewal application, we seek to continue to build our program based on past experience and increase our impact through enhancements designed to formalize the integration between engineering and clinical education in our training program, recruit and enroll a more diverse trainee pool, and strengthen the career development opportunities that facilitate the transition from trainee to independent clinical scientist. Through these innovations and the successful practices we already have in place, we fully expect to continue advancing the science and practice of movement and rehabilitation science by training the next generation of DPT-PhDs in Engineering. We intend to support a total of 6 DPT-PhD students per year during this competitive renewal. The NIH program will provide support for a total of two years of PhD training per trainee. Northwestern will support the first year of training, supplement tuition during the two years of NIH support, and will fully support the DPT training of this unique dual degree training program.

Public Health Relevance

The number of individuals with movement disabilities continues to increase with a clear impact on the need for developing more effective rehabilitation interventions and devices. The continuation of this graduate program will train engineer/clinician scientists combining solid training in fundamental neurobiology and clinical physical therapy with a solid education in the various engineering disciplines. Graduates from this program are expected to advance the field of movement and rehabilitation sciences through basic research and device development.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
2T32EB009406-06A1
Application #
9074421
Study Section
Special Emphasis Panel (ZEB1)
Program Officer
Erim, Zeynep
Project Start
2009-09-01
Project End
2021-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
6
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Physical Medicine & Rehab
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Nelson, Christa M; Murray, Wendy M; Dewald, Julius P A (2018) Motor Impairment-Related Alterations in Biceps and Triceps Brachii Fascicle Lengths in Chronic Hemiparetic Stroke. Neurorehabil Neural Repair 32:799-809
Thompson, Christopher K; Negro, Francesco; Johnson, Michael D et al. (2018) Robust and accurate decoding of motoneuron behaviour and prediction of the resulting force output. J Physiol 596:2643-2659
Binder-Markey, Benjamin I; Murray, Wendy M (2017) Incorporating the length-dependent passive-force generating muscle properties of the extrinsic finger muscles into a wrist and finger biomechanical musculoskeletal model. J Biomech 61:250-257
McPherson, Laura Miller; Negro, Francesco; Thompson, Chris K et al. (2016) Properties of the motor unit action potential shape in proximal and distal muscles of the upper limb in healthy and post-stroke individuals. Conf Proc IEEE Eng Med Biol Soc 2016:335-339
Nelson, Christa M; Dewald, Julius P A; Murray, Wendy M (2016) In vivo measurements of biceps brachii and triceps brachii fascicle lengths using extended field-of-view ultrasound. J Biomech 49:1948-1952
Wilson, Jessica M; Thompson, Christopher K; Miller, Laura C et al. (2015) Intrinsic excitability of human motoneurons in biceps brachii versus triceps brachii. J Neurophysiol 113:3692-9
Hawe, Rachel L; Dewald, Jules P A (2015) Development of a method to quantify inter-limb coupling in individuals with hemiparetic stroke. Conf Proc IEEE Eng Med Biol Soc 2015:3476-9
Abbott, Rebecca; Pedler, Ashley; Sterling, Michele et al. (2015) The geography of fatty infiltrates within the cervical multifidus and semispinalis cervicis in individuals with chronic whiplash-associated disorders. J Orthop Sports Phys Ther 45:281-8
Miller, Laura C; Thompson, Christopher K; Negro, Francesco et al. (2014) High-density surface EMG decomposition allows for recording of motor unit discharge from proximal and distal flexion synergy muscles simultaneously in individuals with stroke. Conf Proc IEEE Eng Med Biol Soc 2014:5340-4
Antos, Stephen A; Albert, Mark V; Kording, Konrad P (2014) Hand, belt, pocket or bag: Practical activity tracking with mobile phones. J Neurosci Methods 231:22-30

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