In 2007, The University of Chicago launched the graduate program in Biophysical Sciences (BPHYS) designed to provide interdisciplinary training at the interface between the physical and biological sciences and promote the University's interdisciplinary research culture.
Aim 1. Establish a nationally-recognized graduate program that will train leaders and pioneers in interdisciplinary exploration.
Aim 2. Promote collaborative research at the interface between the physical and biological sciences as a route to discovery and innovation.
Aim 3. Enhance the culture of The University of Chicago via an interdisciplinary graduate training program that brings together scientific leaders in the scientific community.
Aim 4. Develop and validate an approach to predoctoral training that is individual, student focused, and interdisciplinary and collaborative throughout. In pursuit of these broad aims, several innovative strategies have been incorporated along with many standard elements of a cohesive training program. Ultimately, the engine that will drive program excellence will be a cadre of talented trainees and committed mentors working together to pursue the highest quality science. Innovations: Sophisticated Curriculum. The first year curriculum is built around an intense, year-long practical lab course that teaches the students how to conduct collaborative science and produce, measure &analyze biomolecules using modern biophysical methods. A full-time Curriculum Director is responsible for this practical course and for integrating it with didactic course work, which includes established courses from diverse departments as well as new interdisciplinary courses offered by the Program. Dual Mentorship. Beginning in the second year, each student is a full participant in two active research groups from different scientific fields. For some, this arrangement may simply yield an opportunity to cross fields and become deeply interdisciplinary scientists. Others will initiate new fields of research.

Public Health Relevance

The University of Chicago conducts research in physics, chemistry and biology but in separate departments. This grant supports a new interdepartmental graduate program The primary goal is to train students to apply methods from chemistry and physics to the study of biological and health-related problems

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
5T32EB009412-04
Application #
8264372
Study Section
Special Emphasis Panel (ZEB1-OSR-E (J1))
Program Officer
Baird, Richard A
Project Start
2009-03-01
Project End
2014-02-28
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
4
Fiscal Year
2012
Total Cost
$358,199
Indirect Cost
$17,548
Name
University of Chicago
Department
Biochemistry
Type
Schools of Medicine
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Flanagan, Moira L; Long, Phillip D; Dahlberg, Peter D et al. (2016) Mutations to R. sphaeroides Reaction Center Perturb Energy Levels and Vibronic Coupling but Not Observed Energy Transfer Rates. J Phys Chem A 120:1479-87
Wang, Cheng; Flanagan, Moira L; McGillicuddy, Ryan D et al. (2016) Bacteriophytochrome Photoisomerization Proceeds Homogeneously Despite Heterogeneity in Ground State. Biophys J 111:2125-2134
O'Brien, Sarah L; Gibbons, Sean M; Owens, Sarah M et al. (2016) Spatial scale drives patterns in soil bacterial diversity. Environ Microbiol 18:2039-51
Osinski, Bolesław L; Kay, Leslie M (2016) Granule cell excitability regulates gamma and beta oscillations in a model of the olfactory bulb dendrodendritic microcircuit. J Neurophysiol 116:522-39
Liang, Wenguang G; Triandafillou, Catherine G; Huang, Teng-Yi et al. (2016) Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc Natl Acad Sci U S A 113:5000-5
Gibbons, Sean M; Schwartz, Tara; Fouquier, Jennifer et al. (2015) Ecological succession and viability of human-associated microbiota on restroom surfaces. Appl Environ Microbiol 81:765-73
Stam, Samantha; Alberts, Jon; Gardel, Margaret L et al. (2015) Isoforms Confer Characteristic Force Generation and Mechanosensation by Myosin II Filaments. Biophys J 108:1997-2006
Singh, V P; Westberg, M; Wang, C et al. (2015) Towards quantification of vibronic coupling in photosynthetic antenna complexes. J Chem Phys 142:212446
Wallace, Edward W J; Kear-Scott, Jamie L; Pilipenko, Evgeny V et al. (2015) Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress. Cell 162:1286-98
Constantinides, Michael G; Gudjonson, Herman; McDonald, Benjamin D et al. (2015) PLZF expression maps the early stages of ILC1 lineage development. Proc Natl Acad Sci U S A 112:5123-8

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