Environmental agents play a significant role in the development of human disease. The identification of such toxicants and understanding their causal role in disease can rapidly be used in risk assessment and management and holds enormous promise in terms of preventive, therapeutic and clinical scenarios. This application requests funds to continue NYU's training Program in Environmental and Molecular Toxicology. Specifically, the investigators request funding to support the stipend and tuition of 6 pre-doctoral trainees annually in the NYU Graduate Program in Environmental Health Sciences. The training will address a broad spectrum of problems in environmental health, from the causative molecular mechanisms of cancer, cardiopulmonary diseases, and other environmentally-related disorders to the development of animal models which may be used for predicting the adverse effects of environmental agents on human health. The major strength of the proposed toxicology training program is the outstanding quality and interdisciplinary diversity of the training faculty, which wll provide the pre-doctoral trainees an excellent opportunity to conduct environmental and molecular toxicology research in laboratories of investigators with outstanding international reputations. The mission of this training program is to development creative and independent research scientists who can address the problems presented by complex exposures to environmental pollutants in combination with the stresses of a rapidly changing physical environment.

Public Health Relevance

This application requests continuation of NYU's training program in environmental and molecular toxicology by supporting the annual stipends and tuition of 6 pre-doctoral trainees in environmental health sciences. The mission of this training program is to development creative and independent research scientists who can address the problems presented by complex exposures to environmental pollutants.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007324-18
Application #
9307823
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol A
Project Start
1999-07-01
Project End
2020-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
18
Fiscal Year
2017
Total Cost
Indirect Cost
Name
New York University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10010
Perlmutt, Lars; Stieb, David; Cromar, Kevin (2017) Accuracy of quantification of risk using a single-pollutant Air Quality Index. J Expo Sci Environ Epidemiol 27:24-32
Harrington, Andrea D; Schmidt, Millicent P; Szema, Anthony M et al. (2017) The Role of Iraqi Dust in Inducing Lung Injury in United States Soldiers-An Interdisciplinary Study. Geohealth 1:237-246
Mirowsky, Jaime E; Jin, Lan; Thurston, George et al. (2015) In vitro and in vivo toxicity of urban and rural particulate matter from California. Atmos Environ (1994) 103:256-262
Muñoz, Alexandra; Chervona, Yana; Hall, Megan et al. (2015) Sex-specific patterns and deregulation of endocrine pathways in the gene expression profiles of Bangladeshi adults exposed to arsenic contaminated drinking water. Toxicol Appl Pharmacol 284:330-8
Blum, Jason L; Edwards, Joshua R; Prozialeck, Walter C et al. (2015) Effects of Maternal Exposure to Cadmium Oxide Nanoparticles During Pregnancy on Maternal and Offspring Kidney Injury Markers Using a Murine Model. J Toxicol Environ Health A 78:711-24
Mirowsky, Jaime E; Peltier, Richard E; Lippmann, Morton et al. (2015) Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults. Environ Health 14:66
Amrock, Stephen M; Weitzman, Michael (2014) Effect of increased leptin and C-reactive protein levels on mortality: results from the National Health and Nutrition Examination Survey. Atherosclerosis 236:1-6
Vaughan, Joshua M; Garrett, Brittany J; Prophete, Colette et al. (2014) A novel system to generate WTC dust particles for inhalation exposures. J Expo Sci Environ Epidemiol 24:105-12
Blum, Jason L; Rosenblum, Lauren K; Grunig, Gabriele et al. (2014) Short-term inhalation of cadmium oxide nanoparticles alters pulmonary dynamics associated with lung injury, inflammation, and repair in a mouse model. Inhal Toxicol 26:48-58
Brocato, Jason; Costa, Max (2013) Basic mechanics of DNA methylation and the unique landscape of the DNA methylome in metal-induced carcinogenesis. Crit Rev Toxicol 43:493-514

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