The primary purpose of this broadly based multidisciplinary toxicology and environmental health sciences training program is to prepare trainees for biomedical research careers in schools of medicine, public health, and pharmacy, and in governmental or industrial laboratories with a sound knowledge in environmental health and toxicology. The areas of research emphasis represented by the 22 training faculty include neurotoxicity and neurodegenerative disease, mechanisms of cell death, oxidative DNA damage and repair, and environmental assessment and epidemiology. The 22 members of the training faculty have an established record of success in research training and are currently funded by a total of over $10,000,000 in federal grants with a third of that being from NIEHS. Several scientists from the Centers for Disease Control, including the Agency for Toxic Substances and Diseases Registry, also participate in the training of students through guest lectures and collaborative research. The most important component of training is laboratory research, first as a series of three research rotations, then in the dissertation laboratory. This training is complemented by core courses in toxicology, biochemistry, pharmacology, cell biology, molecular biology, and biostatistics, and advanced courses in toxicology specialty areas, seminar courses, and journal clubs. The program is designed to support six students and three postdoctoral fellows each year from a total eligible population of about 24 students and 30 postdoctoral fellows. The student who completes the pre-doctoral Training Program will have acquired broad familiarity with toxicology and environmental health, knowledge in depth in the area of dissertation research, the ability to search, read critically and report on the literature of the biomedical sciences, mastery of a variety of laboratory techniques useful in modern biomedical research, skill in planning and executing a research project, ability to write clear, accurate scientific reports for publication, and ability to present effectively the results of research. The postdoctoral fellow who completes the Training Program will have gained extensive experience in cutting edge toxicology research, and should have submitted an individual NRSA application to gain grant writing experience to aid in the transition into an independent research position. BACKGROUND This is the first competitive renewal for this Training Program submitted from Emory University. The program is administratively positioned within the Molecular Pharmacology Program (MSP) within the Division of Biological and Biomedical Sciences (DBBS). The goal of the program is to produce broadly trained, competitive scientists oriented towards productive careers related to the toxicological and environmental health sciences. The program is directed by Dr. Gary Miller and co-directed by Dr. Dean Jones. During the first four years of funding, the program has recruited its first classes of pre-doctoral students (total of 12) and postdoctoral fellows (total of 8), expanded the number of participating faculty mentors from 13 to 20, developed a toxicology curriculum within MSP and began the process of establishing the procedures by which students are selected and mentored.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol K
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Emory University
Public Health & Prev Medicine
Schools of Public Health
United States
Zip Code
Radford, Samantha A; Panuwet, Parinya; Hunter Jr, Ronald E et al. (2018) Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment. Toxics 6:
Ladva, Chandresh Nanji; Golan, Rachel; Liang, Donghai et al. (2018) Particulate metal exposures induce plasma metabolome changes in a commuter panel study. PLoS One 13:e0203468
Niedzwiecki, Megan M; Samant, Pradnya; Walker, Douglas I et al. (2018) Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics. Anal Chem 90:3786-3792
Jayaram, Dhanya T; Runa, Sabiha; Kemp, Melissa L et al. (2017) Nanoparticle-induced oxidation of corona proteins initiates an oxidative stress response in cells. Nanoscale 9:7595-7601
Alcock, Ian; White, Mathew P; Taylor, Tim et al. (2017) 'Green' on the ground but not in the air: Pro-environmental attitudes are related to household behaviours but not discretionary air travel. Glob Environ Change 42:136-147
Joers, Valerie; Tansey, MalĂș G; Mulas, Giovanna et al. (2017) Microglial phenotypes in Parkinson's disease and animal models of the disease. Prog Neurobiol 155:57-75
Comstra, Heather S; McArthy, Jacob; Rudin-Rush, Samantha et al. (2017) The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors. Elife 6:
Dennis, Kristine K; Marder, Elizabeth; Balshaw, David M et al. (2017) Biomonitoring in the Era of the Exposome. Environ Health Perspect 125:502-510
Cliburn, Rachel A; Dunn, Amy R; Stout, Kristen A et al. (2017) Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. J Chem Neuroanat 83-84:82-90
Niedzwiecki, Megan M; Miller, Gary W (2017) The Exposome Paradigm in Human Health: Lessons from the Emory Exposome Summer Course. Environ Health Perspect 125:064502

Showing the most recent 10 out of 162 publications