A comprehensive program has been designed with the purpose of training pre-and postdoctoral scientists in the broad area of vision science. Students are participating in graduate and postdoctoral programs in Biochemistry, Computational Biology, Developmental Biology, Human Statistical Genetics, Immunology, Molecular Biophysics, Molecular Cell Biology, Molecular Genetics &Genomics, Microbiology &Microbial Pathogenesis, and Neurosciences. The training program will be delivered by 32 preceptors, 22 of whom are NEI funded, studying nearly all aspects of ocular function and pathology. Predoctoral trainees will take courses that provide detailed information about the neurobiology of the visual system and/or a comprehensive course in all aspects of the development, physiology and pathology of the eye. Postdoctoral trainees are also encouraged to attend these courses. Pre- and postdoctoral trainees are strongly encouraged to participate in the rich environment of seminars, advanced courses, honorary lectures, journal clubs, and retreats offered in the Division of Biology and Biomedical Sciences at Washington University and in the NEI sponsored course, Fundamental Issues in Vision Research. Many of these opportunities involve the participation of both basic and clinical scientists, assuring that trainees will learn about the origins and treatment of human ocular diseases. The training program supports two postdoctoral trainees for their first year at Washington University. This provides adequate time for them to apply for individual research training grant support. The predoctoral training program supports 6 graduate students. This assures that an adequate number of vision science trainees will be available to enrich the training environment. The faculty members in the training program currently have 31 predoctoral and 53 postdoctoral trainees in their laboratories. This demonstrates the commitment of the faculty to training and illustrates the large size of the pool of applicants from which the training grant can draw. The overall goal of this program is to identify the most promising scientists and to provide them with a training environment that maximizes the probability that they will become productive contributors to the understanding and treatment of human ocular diseases.

Public Health Relevance

Talented and well-trained scientists are essential for continued progress in vision research. The goal of this program is to select the best scientists from the large pool of graduate and MD/PhD candidates at Washington University and provide them with training that will prepare them to lead future research in vision.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Institutional National Research Service Award (T32)
Project #
5T32EY013360-13
Application #
8327249
Study Section
Special Emphasis Panel (ZEY1-VSN (11))
Program Officer
Agarwal, Neeraj
Project Start
2000-09-30
Project End
2015-09-29
Budget Start
2012-09-30
Budget End
2013-09-29
Support Year
13
Fiscal Year
2012
Total Cost
$337,905
Indirect Cost
$20,938
Name
Washington University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Klose, Markus; Duvall, Laura B; Li, Weihua et al. (2016) Functional PDF Signaling in the Drosophila Circadian Neural Circuit Is Gated by Ral A-Dependent Modulation. Neuron 90:781-94
Occelli, Laurence M; Tran, Nicholas M; Narfström, Kristina et al. (2016) CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis. Invest Ophthalmol Vis Sci 57:3780-92
Shen, Susan Q; Myers, Connie A; Hughes, Andrew E O et al. (2016) Massively parallel cis-regulatory analysis in the mammalian central nervous system. Genome Res 26:238-55
Kramlinger, Valerie M; Nagy, Leslie D; Fujiwara, Rina et al. (2016) Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids. FEBS Lett 590:1304-12
Lopes, Ricardo J; Johnson, James D; Toomey, Matthew B et al. (2016) Genetic Basis for Red Coloration in Birds. Curr Biol 26:1427-34
Faits, Michelle C; Zhang, Chunmeng; Soto, Florentina et al. (2016) Dendritic mitochondria reach stable positions during circuit development. Elife 5:e11583
Kaul, Aparna; Toonen, Joseph A; Gianino, Scott M et al. (2015) The impact of coexisting genetic mutations on murine optic glioma biology. Neuro Oncol 17:670-7
Enright, Jennifer M; Toomey, Matthew B; Sato, Shin-ya et al. (2015) Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2. Curr Biol 25:3048-57
Xue, Yunlu; Shen, Susan Q; Corbo, Joseph C et al. (2015) Circadian and light-driven regulation of rod dark adaptation. Sci Rep 5:17616
Xue, Yunlu; Shen, Susan Q; Jui, Jonathan et al. (2015) CRALBP supports the mammalian retinal visual cycle and cone vision. J Clin Invest 125:727-38

Showing the most recent 10 out of 84 publications