This proposal is a competitive renewal of a successful and established predoctoral training program whose objective is to broadly train high quality research scientists in basic genetic approaches to the study of biology at the molecular, cellular, organismal, and population level. Funds are requested to support eight trainees each year. Students enter the training program upon admission to the Department of Genetics based on merit and potential for success in scientific careers. Students are rigorously trained in cuttin-edge genetic and biochemical research and data analysis through laboratory research, classes, and attendance at seminars. In addition, they gain written and oral communication skills through preliminary and qualifying examinations;presentations in an annual seminar class, at lab meetings and journal clubs;attendance at national and international meetings;and preparation of manuscripts for publication. Students obtain teaching experience through a requirement to serve as teaching assistants in undergraduate introductory genetics or evolutionary biology for at least one semester in their second or third year. During their first year, students complete three laboratory research rotations as well as participate in lecture courses. All students are required to take at least one course in each of the three broad areas of molecular genetics, genomics and population genetics. The unusual breadth of genetics that students are exposed to throughout their training is a major strength of the program. At the end of their first year, students enter the lab where they will do their dissertation research, choosing from 33 training faculty in nine departments representing a very wide range of genetic disciplines. In years 2-5, students also enroll in seminars, advanced electives and special topics courses. To insure that students complete degree requirements in a timely manner, progress is monitored twice yearly, once by the Graduate Affairs Committee and once by students'dissertation committees. Written and oral examinations and major courses are normally completed by the end of the fifth semester. Graduates from this training program over the past 35+ years have been highly successful in careers in academia, government, and industry. The training program is dynamic and will continue to produce broadly trained leaders in genetics as it embraces the exciting genetic developments of the 21st Century.

Public Health Relevance

This project provides funds to annually support eight Ph.D. students in the field of genetics. It will considerably strengthen the entire graduate program in Genetics at its host institution, the University of Georgia. It will also contribute to public healh in the U.S. by helping train scientists with an exceptionally broad background that includes molecular, population and genomic approaches to genetics.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Carter, Anthony D
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Georgia
Schools of Arts and Sciences
United States
Zip Code
Lee, Byung Ha; Weber, Zachary T; Zourelidou, Melina et al. (2018) Arabidopsis Protein Kinase D6PKL3 Is Involved in the Formation of Distinct Plasma Membrane Aperture Domains on the Pollen Surface. Plant Cell 30:2038-2056
Mason, Jennifer M O; McEachern, Michael J (2018) Mild Telomere Dysfunction as a Force for Altering the Adaptive Potential of Subtelomeric Genes. Genetics 208:537-548
Hofmeister, Brigitte T; Schmitz, Robert J (2018) Enhanced JBrowse plugins for epigenomics data visualization. BMC Bioinformatics 19:159
Ji, Lexiang; Jordan, William T; Shi, Xiuling et al. (2018) TET-mediated epimutagenesis of the Arabidopsis thaliana methylome. Nat Commun 9:895
Dyer, Kelly A; Bewick, Emily R; White, Brooke E et al. (2018) Fine-scale geographic patterns of gene flow and reproductive character displacement in Drosophila subquinaria and Drosophila recens. Mol Ecol :
Lupu, Floria I; Burnett, Jacob B; Eggenschwiler, Jonathan T (2018) Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway. Dev Biol 434:24-35
Valzania, Luca; Coon, Kerri L; Vogel, Kevin J et al. (2018) Hypoxia-induced transcription factor signaling is essential for larval growth of the mosquito Aedes aegypti. Proc Natl Acad Sci U S A 115:457-465
Lower, Sarah E; Stanger-Hall, Kathrin F; Hall, David W (2018) Molecular variation across populations of a widespread North American firefly, Photinus pyralis, reveals that coding changes do not underlie flash color variation or associated visual sensitivity. BMC Evol Biol 18:129
Pieper, Kathleen E; Unckless, Robert L; Dyer, Kelly A (2018) A fast-evolving X-linked duplicate of importin-?2 is overexpressed in sex-ratio drive in Drosophila neotestacea. Mol Ecol 27:5165-5179
Lu, Zefu; Hofmeister, Brigitte T; Vollmers, Christopher et al. (2017) Combining ATAC-seq with nuclei sorting for discovery of cis-regulatory regions in plant genomes. Nucleic Acids Res 45:e41

Showing the most recent 10 out of 75 publications