The enclosed proposal presents a revised training program in genetics at UC Berkeley. The program spans four separate administrative units on the Berkeley campus: the Departments of Molecular &Cell Biology (MCB), Plant &Molecular Biology (PMB), Integrative Biology (IB), and the School of Public Health (PH). The program includes 43 training faculty, all prominent researchers in their respective areas of study (10 are members of the National Academy of Sciences). Training faculty represent three major areas of genetics research: developmental genetics, cell &systems-level analysis, and population genetics &evolution. Funds are requested to support the research activities of 15 graduate student trainees (per year) in genetics-oriented laboratories located within the four aforementioned administrative units. Trainees will be appointed by a steering committee composed of prominent faculty from each of the participating administrative units. This committee is also responsible for renewing the appointments of training faculty and appointing new faculty to the training program. In addition, the committee will review the efficacy of the training program by soliciting comments from past and present trainees and faculty. A number of mechanisms have been established to ensure that the proposed genetics training program offers a unique educational experience that is distinct from other programs on the Berkeley campus, such as genomics, cell &molecular biology, and immunology. First, genetics trainees are required to present their current research findings at an annual retreat that is restricted to trainees and their mentors. Second, all trainees will be required to enroll in at least one advanced genetics course, such as MCB 240. Third, all trainees are required to attend the annual Genetics, Genomics, and Development (GGD) retreat regardless of their departmental affiliations. And fourth, all trainees must participate in at least one additional genetics-oriented forum, such as the weekly GGD seminar series or regularly scheduled journal clubs and research meetings focused on topics in genetic analysis. A variety of outreach strategies will be employed to ensure that members of under- represented minorities, women, and disabled or otherwise disadvantaged students are given the opportunity to obtain training in this program and thereby gain access to the wonderful world of genetics.

Public Health Relevance

Our genes shape who we are. Our health, our susceptibility to disease, and our response to medicines are all affected by our genes. The training of scientists with a firm foundation in formal genetic analysis is essential for understanding how our genes contribute to health and disease.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Carter, Anthony D
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University of California Berkeley
Schools of Arts and Sciences
United States
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Glazer, Andrew M; Cleves, Phillip A; Erickson, Priscilla A et al. (2014) Parallel developmental genetic features underlie stickleback gill raker evolution. Evodevo 5:19
Cleves, Phillip A; Ellis, Nicholas A; Jimenez, Monica T et al. (2014) Evolved tooth gain in sticklebacks is associated with a cis-regulatory allele of Bmp6. Proc Natl Acad Sci U S A 111:13912-7
Erickson, Priscilla A; Glazer, Andrew M; Cleves, Phillip A et al. (2014) Two developmentally temporal quantitative trait loci underlie convergent evolution of increased branchial bone length in sticklebacks. Proc Biol Sci 281:20140822
Cameron, Todd A; Anderson-Furgeson, James; Zupan, John R et al. (2014) Peptidoglycan synthesis machinery in Agrobacterium tumefaciens during unipolar growth and cell division. MBio 5:e01219-14
Bothma, Jacques P; Garcia, Hernan G; Esposito, Emilia et al. (2014) Dynamic regulation of eve stripe 2 expression reveals transcriptional bursts in living Drosophila embryos. Proc Natl Acad Sci U S A 111:10598-603
Beemelmanns, Christine; Woznica, Arielle; Alegado, Rosanna A et al. (2014) Synthesis of the rosette-inducing factor RIF-1 and analogs. J Am Chem Soc 136:10210-3
Dinwiddie, April; Null, Ryan; Pizzano, Maria et al. (2014) Dynamics of F-actin prefigure the structure of butterfly wing scales. Dev Biol 392:404-18
Miller, Craig T; Glazer, Andrew M; Summers, Brian R et al. (2014) Modular skeletal evolution in sticklebacks is controlled by additive and clustered quantitative trait Loci. Genetics 197:405-20
Cohn, Megan; Bart, Rebecca S; Shybut, Mikel et al. (2014) Xanthomonas axonopodis virulence is promoted by a transcription activator-like effector-mediated induction of a SWEET sugar transporter in cassava. Mol Plant Microbe Interact 27:1186-98
Pferdehirt, Rebecca R; Meyer, Barbara J (2013) SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X chromosomes. Proc Natl Acad Sci U S A 110:E3810-9

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