The University of Pennsylvania Medical Scientist Training Program provides support for both MD-PhD and VMD-PhD trainees and is currently in its 37th year of funding. The primary goal of the program is to identify, train and mentor a diverse group of outstanding men and women who will become the leaders of biomedical human and veterinary research, as well as teachers and scholars. To accomplish this goal, we have established flexible training plans that emphasize the integration of the professional and research degrees in preparation for careers that will make use of both. The large institutional commitment to this goal is reflected by the investment that the medical and veterinary schools have made in this program, providing it with resources that are used to help cover tuition and stipend costs, maintain enrichment activities, and support administration of the program. There are currently 220 combined degree students (185 MD-PhD and 25 VMD-PhD), all of whom are fully funded. Admission is open to recent college graduates and to current Penn MD, VMD and PhD students. Selection emphasizes academic excellence, research experience, creativity, letters of recommendation and a well-articulated plan for a career in research. Most trainees do graduate work in the biomedical sciences, but 17% are currently taking advantage of the breadth of opportunities offered by a large university by enrolling in graduate programs in Biomedical Engineering, Physics, Health Care Economics, History &Sociology of Science, Medical Anthropology, Urban Design, and Epidemiology. The proposed training faculty reflects this diversity of interests. It includes 147 senior and junior PhD, MD-PhD and MD investigators in departments, centers and institutes spread across Penn's campus. As of June 2011, there have been 442 MD-PhD and 63 VMD-PhD graduates since program inception. 76% of MD-PhD alumni and 87% of VMD-PhD alumni who have completed postgraduate training are employed by academic centers, research institutes, the biotech and pharmaceutical industries or federal agencies. Many have NIH or other extramural funding for their research. The average time to completion for recent graduates in both programs has been 8 years. The attrition rate for the past 10 years has been low: 4% in the MD-PhD program and 8% in the VMD-PhD program. Specific goals for the next 5 years include 1) continued growth to achieve at least 200 MD-PhD and 30 VMD-PhD students, 2) expanded partnerships with additional graduate programs at Penn, 3) further integration of the graduate and professional degrees, 4) reducing time to degree without compromising training, and 5) attracting and training a diverse group of individuals who will be prepared for the discovery and application of new knowledge through basic, translational and patient-oriented research.

Public Health Relevance

As the pace at which biomedical research advances increases, there is a greater need than ever for physicians and veterinarians who are trained investigators, working at the intersection between medicine and science. The goal of the Medical Scientist Training Program at the University of Pennsylvania is to identify, train and mentor a diverse group of outstanding men and women and to help them become teachers, scholars, and leaders of biomedical research that is relevant to the full spectrum of human and animal disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM007170-39S1
Application #
8699416
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1975-07-01
Project End
2018-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
39
Fiscal Year
2013
Total Cost
$46,691
Indirect Cost
$2,123
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Redding, L E; Cubas-Delgado, F; Sammel, M D et al. (2014) Comparison of two methods for collecting antibiotic use data on small dairy farms. Prev Vet Med 114:213-22
Cho, Nam Woo; Dilley, Robert L; Lampson, Michael A et al. (2014) Interchromosomal homology searches drive directional ALT telomere movement and synapsis. Cell 159:108-21
Fu, Meng-meng; Nirschl, Jeffrey J; Holzbaur, Erika L F (2014) LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes. Dev Cell 29:577-90
Redding, L E; Cubas-Delgado, F; Sammel, M D et al. (2014) The use of antibiotics on small dairy farms in rural Peru. Prev Vet Med 113:88-95
Bajpai, Prachi; Sangar, Michelle C; Singh, Shilpee et al. (2013) Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease. J Biol Chem 288:4436-51
Babushok, Daria V; Li, Yimei; Roth, Jacquelyn J et al. (2013) Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients. Am J Hematol 88:862-7
Ciocca, Maria L; Barnett, Burton E; Burkhardt, Janis K et al. (2012) Cutting edge: Asymmetric memory T cell division in response to rechallenge. J Immunol 188:4145-8
Khandros, Eugene; Thom, Christopher S; D'Souza, Janine et al. (2012) Integrated protein quality-control pathways regulate free ?-globin in murine ?-thalassemia. Blood 119:5265-75
Finkelman, Brian S; Rubinstein, Wendy S; Friedman, Sue et al. (2012) Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers. J Clin Oncol 30:1321-8
Barnett, Burton E; Ciocca, Maria L; Goenka, Radhika et al. (2012) Asymmetric B cell division in the germinal center reaction. Science 335:342-4

Showing the most recent 10 out of 202 publications