Our purpose is to continue and to enhance the Medical Scientist Training Program at the University of Washington. This program provides an opportunity for a group of highly qualified students, selected from a national pool, to pursue the M.D. and Ph.D. degrees concurrently. The overall aim of the program is to provide training for outstanding future medical researchers. Each student is trained in the methodology and logic of basic research as well as the disciplines of medicine. Our expectation is that our trainees will enter careers in medical research and make significant advances in the understanding of human disease processes. A major goal of this program is to achieve a sufficiently large number of MSTP students in each medical school class to establish medical research as major career objectives at the University of Washington. There are several unique features of the program: (1) Our program emphasizes training in molecular biology and bioengineering. (2) New students begin a period of laboratory rotations prior to beginning the fist year medical school curriculum. (3) The second year medical school curriculum occupies mainly afternoons, leaving some mornings free for graduate courses. (4) MSTP students meet regularly on a monthly basis at the school or at faculty homes to present their research and to discuss their future directions. In this program the MSTP student is able to pursue an in-depth research project and medical school studies. Being more intense than either a medical or graduate school program, this experience provides a unique perspective and orientation to medical research. Our overall goal is to train a coterie of excellent students to translate basic molecular research into important medical discoveries.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007266-27
Application #
6350943
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Shapiro, Bert I
Project Start
1975-07-01
Project End
2004-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
27
Fiscal Year
2001
Total Cost
$820,904
Indirect Cost
Name
University of Washington
Department
Pathology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Vandeven, Natalie; Lewis, Christopher W; Makarov, Vladimir et al. (2018) Merkel Cell Carcinoma Patients Presenting Without a Primary Lesion Have Elevated Markers of Immunity, Higher Tumor Mutation Burden, and Improved Survival. Clin Cancer Res 24:963-971
Paulson, Kelly G; Park, Song Youn; Vandeven, Natalie A et al. (2018) Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics. J Am Acad Dermatol 78:457-463.e2
Williams, Katherine L; Wang, Bingjie; Arenz, Dana et al. (2018) Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire. Cell Rep 23:682-691
Campbell, Amy E; Shadle, Sean C; Jagannathan, Sujatha et al. (2018) NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins. Elife 7:
Badeau, Barry A; Comerford, Michael P; Arakawa, Christopher K et al. (2018) Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery. Nat Chem 10:251-258
Wallace, Arianne S; Hudac, Caitlin M; Steinman, Kyle J et al. (2018) Longitudinal report of child with de novo 16p11.2 triplication. Clin Case Rep 6:147-154
Kasinathan, Sivakanthan; Henikoff, Steven (2018) Non-B-Form DNA Is Enriched at Centromeres. Mol Biol Evol 35:949-962
Campbell, Amy E; Belleville, Andrea E; Resnick, Rebecca et al. (2018) Facioscapulohumeral dystrophy: activating an early embryonic transcriptional program in human skeletal muscle. Hum Mol Genet 27:R153-R162
Seo, Aaron; Steinberg-Shemer, Orna; Unal, Sule et al. (2018) Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1. Proc Natl Acad Sci U S A 115:5241-5246
Doud, Michael B; Lee, Juhye M; Bloom, Jesse D (2018) How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin. Nat Commun 9:1386

Showing the most recent 10 out of 404 publications