This application requests continuing support for the University of Iowa Medical Scientist Training Program (MSTP). The goals of the U of Iowa MSTP are to recruit outstanding trainees and provide them with the knowledge base, skills, and inspiration to enable their transition to careers as productive and successful physician-scientists. To accomplish these goals, we have developed an integrated curriculum that assimilates scientific and clinical training and constantly emphasizes the connections and intersections between science and medicine. Students complete 2 years of pre-clinical medical coursework, 3 to 4 years of graduate training, and approximately 18 months of hospital-based clinical clerkships to fulfill the requirements for both the MD and PhD degrees. The Program incorporates several activities throughout the course of study to provide integration and enrichment of the curriculum, program identity, and mentorship of students during transitions in their training. Enrichment and integration activities include Conversations in Research, MSTP Grand Rounds, Clinical Connections, Directors'Dinners, and an annual MSTP Retreat. The Program has 147 talented and diverse faculty members who provide exciting research training opportunities. Students are extensively involved in the MSTP administration, holding positions on the Executive, Admissions, Recruitment and Enrichment &Integration Committees. The Program enjoys strong institutional support from the Dean of the Carver College of Medicine, an active physician-scientist who understands the importance of MSTP training in academic medical centers. The U of Iowa MSTP currently has 67 trainees, of which 40% are women and 13% are from underrepresented minority groups. During the past year, the Program transitioned to a new leadership team of Steven Lentz (Director) and Pamela Geyer (Co-Director). The new Directors share a long-standing passion for mentoring and training physician- scientists. Collectively they have over twenty years of administrative experience in the U of Iowa MSTP. New initiatives focusing on curriculum integration, transitions in training, and recruitment have been formulated through a partnership between students, faculty and the MSTP leadership. Since its inception in 1977, the U of Iowa MSTP has successfully prepared students for careers as physician-scientists. To date, 156 students have graduated and 115 have completed training. The majority of these individuals (74%) are involved in scientific investigation at major academic medical centers. Our graduates are helping to shape the face of academic medicine in leadership roles throughout the country.

Public Health Relevance

The University of Iowa MSTP is committed to the goal of training outstanding students for careers as successful physician-scientists. We aspire to train individuals who will be leaders among the next generation of physician-scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007337-35
Application #
8286160
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1977-07-01
Project End
2016-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
35
Fiscal Year
2012
Total Cost
$844,128
Indirect Cost
$36,084
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Liu, Katherine Y; Sengillo, Jesse D; Velez, Gabriel et al. (2018) Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity. Orphanet J Rare Dis 13:138
Brandt, Kristin E; Falls, Kelly C; Schoenfeld, Joshua D et al. (2018) Corrigendum to: Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells [Redox Biol. (2018) 82-87]. Redox Biol :
Brouillette, Rachel B; Phillips, Elisabeth K; Patel, Radhika et al. (2018) TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus. J Virol 92:
Borcherding, Nicholas; Kolb, Ryan; Gullicksrud, Jodi et al. (2018) Keeping Tumors in Check: A Mechanistic Review of Clinical Response and Resistance to Immune Checkpoint Blockade in Cancer. J Mol Biol 430:2014-2029
Zhang, Michael S; Tran, Phuong M; Wolff, Alexander J et al. (2018) Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters. Sci Signal 11:
Evans, Lucy P; Newell, Elizabeth A; Mahajan, MaryAnn et al. (2018) Acute vitreoretinal trauma and inflammation after traumatic brain injury in mice. Ann Clin Transl Neurol 5:240-251
Kerov, Vasily; Laird, Joseph G; Joiner, Mei-Ling et al. (2018) ?2?-4 Is Required for the Molecular and Structural Organization of Rod and Cone Photoreceptor Synapses. J Neurosci 38:6145-6160
Boland, Lauren; Burand, Anthony J; Brown, Alex J et al. (2018) IFN-? and TNF-? Pre-licensing Protects Mesenchymal Stromal Cells from the Pro-inflammatory Effects of Palmitate. Mol Ther 26:860-873
Chirco, Kathleen R; Lewis, Carly J; Scheetz, Todd E et al. (2018) Evaluation of sFLT1 protein levels in human eyes with the FLT1 rs9943922 polymorphism. Ophthalmic Genet 39:68-72
Weeks, Kristin S; Kahl, Amanda R; Lynch, Charles F et al. (2018) Racial/ethnic differences in thyroid cancer incidence in the United States, 2007-2014. Cancer 124:1483-1491

Showing the most recent 10 out of 508 publications