The goal of the University of Michigan Medical Scientist Training Program is to train physician scientists primarily for careers in academic medicine with a focus on basic biomedical research. Such individuals are uniquely positioned to bridge the gap between basic and clinical medicine, and hence to connect basic discoveries to improvements in human health. The U of Michigan Medical Center is one of the world's largest one-site complexes devoted to health education, research and patient care. There are over 2.6 million sq ft of space dedicated to education and laboratory research. The Michigan MSTP provides an integrated curriculum of M.D./Ph.D. training. Matriculants have a strong history of academic success and research experience, and are graduates of outstanding colleges from all parts of the U.S. There are currently 82 trainees and 141 graduates. The curriculum begins with the two basic science years of medical school. A graduate level biochemistry course is taken as part of the 1st year of medical school. Trainees undertake a research rotation after the 1st year of medical school and one or two rotations after the 2nd year. Trainees select a Ph.D. field during the 2nd year of medical school;core participating departments include Bioinformatics, Biological Chemistry, Biophysics, Cell &Developmental Biology, Cellular &Molecular Biology, Chemical Biology, Human Genetics, Immunology, Medicinal Chemistry, Microbiology &Immunology, Molecular &Cellular Pathology, Molecular &Integrative Physiology, Neuroscience, and Pharmacology. Other fields are possible;for example, currently there are trainees in several departments in our Schools of Engineering and Public Health. Trainees take a leave of absence from medical school typically after the 2nd year or after the first 3 months of the 3rd year to continue graduate studies full time. Trainees can participate in clinical preceptorships during their research years. Upon successful completion of the thesis defense, trainees complete their clinical training. The 3rd year of medical school can be entered any month within the first half of the academic year to accommodate variations in thesis defense dates, and the 4th year of medical school is truncated to 20 weeks. Total training is typically 7 to 8 years. There are monthly program activities including seminars, social events and an annual scientific retreat.

Public Health Relevance

Trainees receive both an M.D. and a Ph.D. in a medically-relevant field of research. Program graduates are optimally prepared to establish research-based careers in which the goal is to improve the public's health.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007863-35
Application #
8686863
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter
Project Start
1980-08-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
35
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Lyons, Daniel M; Lauring, Adam S (2018) Mutation and Epistasis in Influenza Virus Evolution. Viruses 10:
Markovitz, Adam A; Hofer, Timothy P; Froehlich, Whit et al. (2018) An Examination of Deintensification Recommendations in Clinical Practice Guidelines: Stepping Up or Scaling Back? JAMA Intern Med 178:414-416
Anwar, Talha; Arellano-Garcia, Caroline; Ropa, James et al. (2018) p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis. Nat Commun 9:2801
Fujiwara, Hideaki; Docampo, Melissa D; Riwes, Mary et al. (2018) Microbial metabolite sensor GPR43 controls severity of experimental GVHD. Nat Commun 9:3674
Schofield, Heather K; Tandon, Manuj; Park, Min-Jung et al. (2018) Pancreatic HIF2? Stabilization Leads to Chronic Pancreatitis and Predisposes to Mucinous Cystic Neoplasm. Cell Mol Gastroenterol Hepatol 5:169-185.e2
Allison, Margaret B; Pan, Warren; MacKenzie, Alexander et al. (2018) Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action. Diabetes 67:1093-1104
Bagchi, Devika P; Forss, Isabel; Mandrup, Susanne et al. (2018) SnapShot: Niche Determines Adipocyte Character II. Cell Metab 27:266-266.e1
Lu, Kevin L; Nelson, Jonathan O; Watase, George J et al. (2018) Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells. Elife 7:
Giles, David A; Washnock-Schmid, Jesse M; Duncker, Patrick C et al. (2018) Myeloid cell plasticity in the evolution of central nervous system autoimmunity. Ann Neurol 83:131-141
Antonellis, Anthony; Oprescu, Stephanie N; Griffin, Laurie B et al. (2018) Compound heterozygosity for loss-of-function FARSB variants in a patient with classic features of recessive aminoacyl-tRNA synthetase-related disease. Hum Mutat 39:834-840

Showing the most recent 10 out of 402 publications