The Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS) at Columbia University Medical Center is a Ph.D. granting program that combines faculty from all the basic science departments. The CMBS Program is an umbrella program that presents students with a unique opportunity to obtain individualized training in basic cell and molecular biology, microbiology, structural biology, biophysics, genetics, immunology, neurobiology, computational biology, as well as translational biomedical disease-related research. Our hope is to train the next leaders in the field of biomedical research and also to provide training for future leaders in other areas where a biomedical research background will be of great benefit. The CMBS program is an accredited degree-granting program that was first established in 1986 and has been supported by this Training Grant since 1987. The program has a distinguished, well- funded faculty of 135 trainers, whose research expertise represents nearly all the areas of modern cellular and molecular biology, neurobiology and computational biology. There are currently 69 students in this program. Seventy two students have graduated from the CMBS Program in the past five years and have gone on to postdoctoral positions in outstanding laboratories, careers in the pharmaceutical of biotechnology industry, or careers where they use their biomedical training to provide other societal benefits. Students take core courses in molecular genetics, molecular and cell biology as well as statistics during their first year and complete three laboratory rotations. In the secod year, students take their qualifying examination and a course in the Responsible Conduct of Research. The CMBS Program hosts a student research seminar series and a biennial student-faculty retreat. Most students graduated in 5-6 years. The CMBS Program remains the premier cellular and molecular biology graduate program at Columbia University Medical Center and support from this Training Grant is crucial for the continued success of this program.

Public Health Relevance

The goal of this program is to provide students with a unique opportunity to obtain individualized training in basic cell and molecular biology, microbiology, structural biology, biophysics, genetics, immunology, neurobiology, computational biology, as well as translational biomedical disease-related research.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008224-28
Application #
8694045
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
Project End
Budget Start
Budget End
Support Year
28
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Pathology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10032
Codega, Paolo; Silva-Vargas, Violeta; Paul, Alex et al. (2014) Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche. Neuron 82:545-59
Worthley, Daniel L; Si, Yiling; Quante, Michael et al. (2013) Bone marrow cells as precursors of the tumor stroma. Exp Cell Res 319:1650-6
Li, Darrick K; Tisdale, Sarah; Espinoza-Derout, Jorge et al. (2013) A cell system for phenotypic screening of modifiers of SMN2 gene expression and function. PLoS One 8:e71965
Tisdale, Sarah; Lotti, Francesco; Saieva, Luciano et al. (2013) SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3'-end formation of histone mRNAs. Cell Rep 5:1187-95
Canetta, Sarah E; Luca, Edlira; Pertot, Elyse et al. (2011) Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation. PLoS One 6:e25108
Jabado, Omar J; Conlan, Sean; Quan, Phenix-Lan et al. (2010) Nonparametric methods for the analysis of single-color pathogen microarrays. BMC Bioinformatics 11:354
Tung, Jennifer J; Hobert, Oliver; Berryman, Mark et al. (2009) Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro. Angiogenesis 12:209-20
Jabado, Omar J; Liu, Yang; Conlan, Sean et al. (2008) Comprehensive viral oligonucleotide probe design using conserved protein regions. Nucleic Acids Res 36:e3
Mozlin, Amy M; Fung, Cindy W; Symington, Lorraine S (2008) Role of the Saccharomyces cerevisiae Rad51 paralogs in sister chromatid recombination. Genetics 178:113-26
Kvajo, Mirna; McKellar, Heather; Arguello, P Alexander et al. (2008) A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci U S A 105:7076-81

Showing the most recent 10 out of 21 publications