The UCLA Intercampus Medical Genetics Postdoctoral Training Program is a university-wide training program which uses the faculty and facilities of three UCLA medical campuses: Cedars-Sinai Medical Center, Harbor-UCLA Medical Center, and the Center for Health Sciences (UCLA). The fellowship training program is directed toward the training of postdoctoral MD, PhD, and DDS candidates who are highly motivated toward academic research careers in the field of medical genetics. The basic aim of the training program is to train individuals with a broad knowledge in medical genetics and an intensive experience in genetic research so they may enter the academic community as independent investigators. The program brings together the many faculty members interested in medical genetics from the School of Medicine's basic science departments, the University's Molecular Biology Institute, and the Medical Genetics units of the three UCLA hospitals. The trainees supported by this postdoctoral training program are given a broad experience in medical genetics and intensive research training in molecular, mathematical and/or medical genetics. They attend educational seminars with trainees in clinical genetics supported by hospital funds, as well as with other basic science postdoctoral research fellows who are mentored by the faculty of this training program. The funding of this NIH training program has led to a 3-hour weekly educational program, held throughout the academic year, a Research retreat, and visiting professor programs, which bring together postdoctoral trainees of many diverse backgrounds. Students from this research training program interact with trainees from many basic science departments and the Molecular Biology Institute who are doing pure basic research training, as well as clinical trainees from the individual hospital programs in medical genetics. It has also brought together faculty from basic science and clinical departments, resulting in a joint awareness of their interests and expertise that has led to many new collaborative studies. The trainees may obtain their research training with mentors in either the basic science departments or in clinical departments. If they choose research training by faculty in clinical departments, they will be expected to perform a hypothesis-driven research project under the guidance of that individual faculty member, or at times, in collaboration with a member of one of the basic science departments. This program has attracted many MD and PhD postdoctoral trainees over the past 20 years who have gone on to productive academic research careers.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008243-25
Application #
8110703
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (PG))
Program Officer
Haynes, Susan R
Project Start
1987-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
25
Fiscal Year
2011
Total Cost
$223,055
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Kan, Shih-Hsin; Le, Steven Q; Bui, Quang D et al. (2016) Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice. Behav Brain Res 312:265-71
Wang, Jessica Jen-Chu; Rau, Christoph; Avetisyan, Rozeta et al. (2016) Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. PLoS Genet 12:e1006038
Lee, Patrick C; Truong, Brian; Vega-Crespo, Agustin et al. (2016) Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. Mol Ther Nucleic Acids 5:e394
Tai, Denise S; Hu, Chuhong; Kim, Elizabeth H et al. (2015) Augmentation of transgene-encoded protein after neonatal injection of adeno-associated virus improves hepatic copy number without immune responses. Pediatr Res 78:239-246
Hu, C; Tai, D S; Park, H et al. (2015) Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy. Gene Ther 22:111-5
Rickabaugh, Tammy M; Baxter, Ruth M; Sehl, Mary et al. (2015) Acceleration of age-associated methylation patterns in HIV-1-infected adults. PLoS One 10:e0119201
Provenzale, James M; Nestrasil, Igor; Chen, Steven et al. (2015) Diffusion tensor imaging and myelin composition analysis reveal abnormal myelination in corpus callosum of canine mucopolysaccharidosis I. Exp Neurol 273:1-10
Baxter, Ruth M; Arboleda, Valerie A; Lee, Hane et al. (2015) Exome sequencing for the diagnosis of 46,XY disorders of sex development. J Clin Endocrinol Metab 100:E333-44
Tai, D S; Hu, C; Lee, C C I et al. (2015) Development of operational immunologic tolerance with neonatal gene transfer in nonhuman primates: preliminary studies. Gene Ther 22:923-30
Kan, Shih-hsin; Troitskaya, Larisa A; Sinow, Carolyn S et al. (2014) Insulin-like growth factor II peptide fusion enables uptake and lysosomal delivery of ?-N-acetylglucosaminidase to mucopolysaccharidosis type IIIB fibroblasts. Biochem J 458:281-9

Showing the most recent 10 out of 124 publications