Our training program major goal or objective is to provide an educational environment to young physicians and/or scientists interested in academic research in the areas of burns and trauma. Our training program is an integrated two year research experience which offers the trainee highly-structured research training in fundamental aspects of molecular biology, physiology, biochemistry, metabolism, immunology and cell biology as they pertain to the pathophysiologic state post burn. The program includes basic or bench research, animal research and human or clinical studies in which the concepts of interpreting basic information from the laboratory and applying it to clinical problems and clinical research are taught. Our program aims to train burn fellows in research through hands-on experiments in highly productive environments. Our methods will involve presentations by the trainees of their work at local internal meetings, grand rounds, and national and international meetings with the aim of developing and enhancing scientific writing skills and thought processes essential for abstract and manuscript preparation, and eventually vital for intramural or extramural grant proposals. Finally, our training program also aims to promote and assist research fellows in obtaining academic positions in environments commensurate with their training and interests and further their career development. The trainee, guided by junior and senior faculty will focus their efforts to address problems pertinent to improving survival and the quality of life of burned children. Findings developed from the research activities by our trainees will continue to advance burn care worldwide. Our training program is multidisciplinary and involves physicians and scientists. Each trainee is mentored by one or two faculty. Trainees are evaluated in part by number of publications, presentations at meetings and near the end of their training experience, are encouraged to apply for federal grants to further their careers as independent researchers.

Public Health Relevance

Findings developed from the research activities by our trainees will advance burn care worldwide. Trainees will go on to become clinicians and scientists who will provide health care or be involved in healthcare activities, whether research, clinical or medical activities that are relevant and directly impact public health. Finally, our trainees will also be mentors of other trainees who will continue the educational cycle and impact public health.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZGM1-BRT-5 (PD))
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Somers, Scott D
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University of Texas Medical Br Galveston
Schools of Medicine
United States
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Kraft, Robert; Herndon, David N; Finnerty, Celeste C et al. (2015) Predictive Value of IL-8 for Sepsis and Severe Infections After Burn Injury: A Clinical Study. Shock 43:222-7
Diaz, Eva C; Herndon, David N; Porter, Craig et al. (2015) Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns. Burns 41:649-57
Jeschke, Marc G; Pinto, Ruxandra; Herndon, David N et al. (2014) Hypoglycemia is associated with increased postburn morbidity and mortality in pediatric patients. Crit Care Med 42:1221-31
Peterson, Jonathan R; De La Rosa, Sara; Eboda, Oluwatobi et al. (2014) Treatment of heterotopic ossification through remote ATP hydrolysis. Sci Transl Med 6:255ra132
Jeschke, Marc G; Gauglitz, Gerd G; Finnerty, Celeste C et al. (2014) Survivors versus nonsurvivors postburn: differences in inflammatory and hypermetabolic trajectories. Ann Surg 259:814-23
Porter, Craig; Herndon, David N; Børsheim, Elisabet et al. (2014) Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults. Am J Physiol Endocrinol Metab 307:E462-7
Rehberg, Sebastian; Yamamoto, Yusuke; Sousse, Linda E et al. (2014) Advantages and pitfalls of combining intravenous antithrombin with nebulized heparin and tissue plasminogen activator in acute respiratory distress syndrome. J Trauma Acute Care Surg 76:126-33
Kraft, Robert; Herndon, David N; Mlcak, Ronald P et al. (2014) Bacterial respiratory tract infections are promoted by systemic hyperglycemia after severe burn injury in pediatric patients. Burns 40:428-35
Chondronikola, Maria; Meyer, Walter J; Sidossis, Labros S et al. (2014) Predictors of insulin resistance in pediatric burn injury survivors 24 to 36 months postburn. J Burn Care Res 35:409-15
Kraft, Robert; Herndon, David N; Finnerty, Celeste C et al. (2014) Occurrence of multiorgan dysfunction in pediatric burn patients: incidence and clinical outcome. Ann Surg 259:381-7

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