Continuation of an ongoing interdisciplinary graduate training program in molecular biophysics at the University of Washington is sought. Support for the training of 12 predoctoral students per year is requested. Trainees will be selected competitively from a pool of approximately 100 students who enter the university through ten departments or programs (Biochemistry, Bioengineering, Biomolecular Structure &Design, Chemistry, Medicinal Chemistry, Molecular &Cellular Biology, Medical Scientist Training Program, Microbiology, Pharmacology, and Physiology &Biophysics). Trainee research will be conducted in twenty-nine faculty laboratories housed on the UW campus and at Fred Hutchison Cancer Research Center. Trainees will be exposed to modern molecular biophysics through interdisciplinary course, seminars, and specialized thesis research. Cross-disciplinary training is encouraged through dual mentorship and collaborative research projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008268-25
Application #
8496046
Study Section
Special Emphasis Panel (ZGM1-BRT-X (TG))
Program Officer
Flicker, Paula F
Project Start
1988-09-30
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
25
Fiscal Year
2013
Total Cost
$308,910
Indirect Cost
$19,103
Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hsu, Peter L; Yang, Fan; Smith-Kinnaman, Whitney et al. (2014) Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD. J Mol Biol 426:2970-81
Leonard, Stephen E; Register, A C; Krishnamurty, Ratika et al. (2014) Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors. ACS Chem Biol 9:1894-905
Tang, Lin; Gamal El-Din, Tamer M; Payandeh, Jian et al. (2014) Structural basis for Ca2+ selectivity of a voltage-gated calcium channel. Nature 505:56-61
Finton, Kathryn A K; Friend, Della; Jaffe, James et al. (2014) Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10. PLoS Pathog 10:e1004403
Register, A C; Leonard, Stephen E; Maly, Dustin J (2014) SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family. Biochemistry 53:6910-23
Umbreit, Neil T; Miller, Matthew P; Tien, Jerry F et al. (2014) Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation. Nat Commun 5:4951
Conway, Patrick; Tyka, Michael D; DiMaio, Frank et al. (2014) Relaxation of backbone bond geometry improves protein energy landscape modeling. Protein Sci 23:47-55
Teller, David C; Behnke, Craig A; Pappan, Kirk et al. (2014) The structure of rice weevil pectin methylesterase. Acta Crystallogr F Struct Biol Commun 70:1480-4
Stanich, Cynthia A; Honerkamp-Smith, Aurelia R; Putzel, Gregory Garbes et al. (2013) Coarsening dynamics of domains in lipid membranes. Biophys J 105:444-54
Delbecq, Scott P; Klevit, Rachel E (2013) One size does not fit all: the oligomeric states of ?B crystallin. FEBS Lett 587:1073-80

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