To train the next generation of scientists, the Christopher S. Bond Life Sciences Center at the University of Missouri, in conjunction with the Departments of Biochemistry, Biological Sciences, Molecular Microbiology and Immunology (MMI), the Pathobiology Area Program (PAP) and the MU Informatics Institute (MUII), have developed a collaborative training program in the Molecular Life Sciences. This proposal requests continued support from the National Institute for General Medical Sciences for a training grant on the Molecular Basis of Gene Expression and Signal Processing. This training grant provides funding to support six trainees per year. The 45 participating faculty members in this training program comprise a select group of outstanding scientists selected from the three departments and two interdisciplinary training programs at MU. Students in this program will participate in a training program that has both department-specific and program-wide components. The departmental components include (1) a set of departmental-specific classes that provide a curriculum appropriate for the particular disciplinary interests of each Fellow, (2)a group of outstanding scientists as mentors and role models for both disciplinary and interdisciplinary research and (3) the opportunity for the Fellows to develop their own skills as teachers by serving as Teaching Assistants or as research mentors to undergraduates. The program-wide components include (4) two required core classes, one in molecular biology and one in bioinformatics, that provide a common foundation in molecular and cellular biology, (5) a student-driven seminar program that provides a broad perspective across diverse scientific disciplines, peer-to-peer interactions and an opportunity to improve oral communication skills, (6) instruction in written communication so that our trainees will acquire skills in manuscript writing and grant preparation needed for their subsequent career, and (7) travel funds that enable our young scientists to present their work at national and international meetings. Working together, these departmental-specific and program-wide components provide our graduate students with both a depth of disciplinary expertise and a breadth of exposure to other disciplines that will enable our graduates to be the scientific leaders of the future.
Biomedical research has the potential to improve human health and reduce pain and suffering caused by disease. However, the questions that drive biomedical research are no longer bounded by the traditional disciplines in the physical and biological sciences. We propose to train the next generation of biomedical scientists, equipping them with deep expertise in a particular discipline and the ability to communicate and collaborate with other scientists across disciplinary boundaries.
|Stiers, Kyle M; Lee, Christopher B; Nix, Jay C et al. (2016) Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course. J Appl Crystallogr 49:2235-2243|
|Prior, Stephen H; Byrne, Todd S; Tokmina-Roszyk, Dorota et al. (2016) Path to Collagenolysis: COLLAGEN V TRIPLE-HELIX MODEL BOUND PRODUCTIVELY AND IN ENCOUNTERS BY MATRIX METALLOPROTEINASE-12. J Biol Chem 291:7888-901|
|Northcutt, Adam J; Lett, Kawasi M; Garcia, Virginia B et al. (2016) Deep sequencing of transcriptomes from the nervous systems of two decapod crustaceans to characterize genes important for neural circuit function and modulation. BMC Genomics 17:868|
|Taylor, Isaiah; Wang, Ying; Seitz, Kati et al. (2016) Analysis of Phosphorylation of the Receptor-Like Protein Kinase HAESA during Arabidopsis Floral Abscission. PLoS One 11:e0147203|
|Lane, Brian J (2016) A leech model for homeostatic plasticity and motor network recovery after loss of descending inputs. J Neurophysiol 115:1752-4|
|Salie, Matthew J; Zhang, Ning; Lancikova, Veronika et al. (2016) A Family of Negative Regulators Targets the Committed Step of De novo Fatty Acid Biosynthesis. Plant Cell :|
|Lane, Brian J; Samarth, Pranit; Ransdell, Joseph L et al. (2016) Synergistic plasticity of intrinsic conductance and electrical coupling restores synchrony in an intact motor network. Elife 5:|
|VillalÃ³n, Eric; Dale, Jeffrey M; Jones, Maria et al. (2015) Exacerbation of Charcot-Marie-Tooth type 2E neuropathy following traumatic nerve injury. Brain Res 1627:143-53|
|Dhakal, Mermagya; Miller, Mindy M; Zaghouani, Adam A et al. (2015) Neonatal Basophils Stifle the Function of Early-Life Dendritic Cells To Curtail Th1 Immunity in Newborn Mice. J Immunol 195:507-18|
|Spencer, Matt; Eickholt, Jesse; Jianlin Cheng (2015) A Deep Learning Network Approach to ab initio Protein Secondary Structure Prediction. IEEE/ACM Trans Comput Biol Bioinform 12:103-12|
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