A Medical Scientist Training Program (MSTP) is offered by Stony Brook University (SBU) in conjunction with Brookhaven National Laboratory and Cold Spring Harbor Laboratory. The purpose of the MSTP is to train academic medical scientists for both research and teaching in medical schools and research institutions. Graduates of the program (63 to date) are equipped to study major medical problems at the basic science level and to recognize the clinical significance of their pursuits and discoveries. Of our 61 graduates since 1990, many are in faculty positions at prestigious institutions throughout the U.S., including 3 Instructors, 11 Assistant Professors, and 4 Associate Professors. Most of these have been awarded K08, ROI, and / or POI competitive research funding from the NIH or other sources and have demonstrated research productivity since leaving SBU, in many cases with first or senior author publications in top journals such as Science, Nature, Nature Genetics, Nature Medicine, J. Clin. Invest, and Immunity. Most of the 37 graduates who received training grant support (starting with the entering class of 1992) are still in training and only 2 (6%) are in private practice. Graduate Programs in which the Ph.D. may be earned include Applied Math, Biochemistry and Structural Biology, Genetics, Molecular and Cellular Biology, Pharmacology, Microbiology, Neurobiology and Behavior, Physiology and Biophysics, and Biomedical Engineering. Each program is an independent doctoral degree- granting unit. Initiatives underway at SBU include ones in proteomics, diabetes, computational neurobiology, expansion of the hospital, and development of a cancer center. Finally, our small MSTP has diversity and flexibility that permits the design of individualized educational opportunities to meet the needs of trainees with a variety of interests, backgrounds and career goals. We anticipate 7-8 years of training to complete the MD and PhD degrees (of which this training grant will support 3 years per student). We request support for 18 trainees (out of a total of 50 projected to be in the program). The students recruited will have extensive prior research experience.

Public Health Relevance

Training of physician-scientists is vital to bring discoveries made at the bench to the bedside, i.e. to have an impact on human health. This program will give rigorous scientific and medical training to highly talented students so that they can take advantage of scientific opportunities to devise and apply new types of health care, or use their medical knowledge to recognize and answer scientific questions that will advance our understanding of human physiology and create new possibilities for therapeutic intervention.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008444-20
Application #
8102886
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1992-07-01
Project End
2015-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
20
Fiscal Year
2011
Total Cost
$259,488
Indirect Cost
Name
State University New York Stony Brook
Department
Pharmacology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Miyauchi, Jeremy Tetsuo; Caponegro, Michael D; Chen, Danling et al. (2018) Deletion of Neuropilin 1 from Microglia or Bone Marrow-Derived Macrophages Slows Glioma Progression. Cancer Res 78:685-694
Werneburg, Glenn T; Kongnyuy, Michael; Halpern, Daniel M et al. (2018) Effects of Focal vs Total Cryotherapy and Minimum Tumor Temperature on Patient-reported Quality of Life Compared With Active Surveillance in Patients With Prostate Cancer. Urology 113:110-118
Werneburg, Glenn T; Kongnyuy, Michael; Halpern, Daniel M et al. (2018) Patient-reported quality of life progression in men with prostate cancer following primary cryotherapy, cyberknife, or active holistic surveillance. Prostate Cancer Prostatic Dis 21:355-363
Schneider, Michael; Kumar, Vivek; Nordstrøm, Lars Ulrik et al. (2018) Inhibition of Delta-induced Notch signaling using fucose analogs. Nat Chem Biol 14:65-71
Werneburg, Glenn T; Thanassi, David G (2018) Pili Assembled by the Chaperone/Usher Pathway in Escherichia coli and Salmonella. EcoSal Plus 8:
Nomakuchi, Tomoki T; Rigo, Frank; Aznarez, Isabel et al. (2016) Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nat Biotechnol 34:164-6
Rubin, Ewelina; Werneburg, Glenn T; Pales Espinosa, Emmanuelle et al. (2016) Identification and characterization of peptidases secreted by quahog parasite unknown (QPX), the protistan parasite of hard clams. Dis Aquat Organ 122:21-33
Huculeci, Radu; Cilia, Elisa; Lyczek, Agatha et al. (2016) Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure 24:1947-1959
Park, Juwon; Wysocki, Robert W; Amoozgar, Zohreh et al. (2016) Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med 8:361ra138
Bhagwat, Anand S; Roe, Jae-Seok; Mok, Beverly Y L et al. (2016) BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements. Cell Rep 15:519-530

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