This proposal is for the third competitive renewal of the training grant,""""""""Predoctoral Training of Neuroscientists"""""""", 5T32 GM008471, at the University of Minnesota. Trainees in this program are pursuing a Ph.D. through the Graduate Program in Neuroscience. The challenge ahead is to train neuroscientists who possess the diverse knowledge and research skills required by this highly multidisciplinary, rapidly changing field. The mission of this training program is to train outstanding neuroscientists who will be prepared for successful careers in academic research and teaching, industry and government/public service. The objective is to provide students with broad fundamentals of neuroscience and in-depth research experience. The proposed training program will fund predoctoral students primarily during their second year in the Graduate Program in Neuroscience. The program is built around a core of didactic coursework in neuroscience, dissertation research, and exposure to neuroscience on the national level. Flexibility and time for in-depth development of collateral fields of knowledge and research skills are provided. Several unique educational opportunities are available, and time and attention are given to the students'professional development. A group of 65 trainers is proposed that reflects the diversity of the areas of study and research techniques in neuroscience. Research interests range from the cellular and molecular to the systems and behavior levels. Each trainer directs a productive research program and has demonstrated commitment to teaching and training. Representing 9 colleges and 20 departments throughout the University, the trainers are united by their participation in the Graduate Program in Neuroscience. An impressive array of scientific and institutional resources is available to the trainees. Relevance: The graduates of this program will have been trained with a strong, broad foundation in neuroscience as well as the interdisciplinary skills needed for the neuroscience workforce of tomorrow. Trained to be independent researchers, the graduates will serve the health care needs of the nation in academics, teaching, industry, government and public service.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008471-20
Application #
8290348
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (TG))
Program Officer
Maas, Stefan
Project Start
1993-07-01
Project End
2013-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
20
Fiscal Year
2012
Total Cost
$283,199
Indirect Cost
$16,980
Name
University of Minnesota Twin Cities
Department
Neurosciences
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Zick, Jennifer L; Blackman, Rachael K; Crowe, David A et al. (2018) Blocking NMDAR Disrupts Spike Timing and Decouples Monkey Prefrontal Circuits: Implications for Activity-Dependent Disconnection in Schizophrenia. Neuron 98:1243-1255.e5
Legon, Wynn; Bansal, Priya; Tyshynsky, Roman et al. (2018) Transcranial focused ultrasound neuromodulation of the human primary motor cortex. Sci Rep 8:10007
Sweis, Brian M; Abram, Samantha V; Schmidt, Brandy J et al. (2018) Sensitivity to ""sunk costs"" in mice, rats, and humans. Science 361:178-181
Khan, Shahzad S; LaCroix, Michael; Boyle, Gabriel et al. (2018) Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathol :
Tonn Eisinger, Katherine R; Gross, Kellie S; Head, Brian P et al. (2018) Interactions between estrogen receptors and metabotropic glutamate receptors and their impact on drug addiction in females. Horm Behav :
Ferro, Austin; Qu, Wenhui; Lukowicz, Abigail et al. (2018) Inhibition of NF-?B signaling in IKK?F/F;LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1. PLoS One 13:e0200013
Tonn Eisinger, Katherine R; Larson, Erin B; Boulware, Marissa I et al. (2018) Membrane estrogen receptor signaling impacts the reward circuitry of the female brain to influence motivated behaviors. Steroids 133:53-59
Sweis, Brian M; Thomas, Mark J; Redish, A David (2018) Mice learn to avoid regret. PLoS Biol 16:e2005853
Sweis, Brian M; Larson, Erin B; Redish, A David et al. (2018) Altering gain of the infralimbic-to-accumbens shell circuit alters economically dissociable decision-making algorithms. Proc Natl Acad Sci U S A 115:E6347-E6355
Montgomery, Jacob E; Wahlstrom-Helgren, Sarah; Wiggin, Timothy D et al. (2018) Intraspinal serotonergic signaling suppresses locomotor activity in larval zebrafish. Dev Neurobiol :

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