Funding for the support of six trainee positions is requested for the Duke University Program in Structural Biology and Biophysics. The Program currently consists of twenty-five faculty and twenty-two trainees based in three different departments. Training goals include: 1) didactic instruction in biomolecular structure and function, principles of biophysical methods and analysis, conformational analysis;2) broad, interdisciplinary exposure to biophysical research in multiple research laboratory environments;3) trainee-designed original dissertation research with frequent faculty feedback;4) regular teaching and speaking opportunities. These goals are accomplished by providing program students with an intellectual home via weekly research seminars, faculty committee oversight and other informal scientific interactions. About half of the training grant supported trainees enter the program as first year graduate students and are supported through the summer of their second year. The other half of supported trainees enter through participating departments and are supported in their second and/or third years. A large fraction of program trainees are not supported by the training grant but nevertheless are full participants and receive certificates in Structural Biology and Biophysics when they graduate. Students conduct three seven week laboratory rotations, then select a dissertation advisor. The trainees then fulfill the degree requirements of the advisor's home department. If they continue to participate in the program, trainees receive a Certificate in Structural Biology at the time of graduation. A key training component is a weekly seminar series consisting of both student and faculty talks. The SBB program represents the intellectual and academic home of a growing and active community of structural biologists and biophysicists at Duke.

Public Health Relevance

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Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008487-16A1
Application #
7764250
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Flicker, Paula F
Project Start
1994-07-01
Project End
2015-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
16
Fiscal Year
2010
Total Cost
$218,672
Indirect Cost
Name
Duke University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
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