Opportunities in the fields of genetics and molecular biology in academia, government, and in the private sector have increased with the incredible acquisition of genetic information and the potential to use this information for developing novel medical therapies and diagnostic procedures. To use this information both today and in the future, there is a need to train the next generation of geneticists and molecular biologists with fundamental and cutting-edge skills. With this in mind, the goal and philosophy of this PhD training program is to provide the best training in a particular core area of genetics and molecular biology while at the same time providing broad-based training in the related disciplines of biochemistry, cell biology, statistics, and bioinformatics. Students whose aspirations best match this training philosophy will be selected for support by this training program. This training program draws its faculty and students from the interdepartmental graduate program in Genetics and Molecular Biology (GMB). The GMB program is highly interdisciplinary with its faculty coming from the ranks of 11 basic science and clinical departments. We have requested 9-11 positions for this training program, for which students will be supported for 2-3 years depending on their achievements and success. This number represents about 20% of the total students within the parent GMB graduate program. Our students will have opportunities to perform genetics research in six core areas, including Bioinformatics and Comparative Genomics, Cancer Genetics;Control of Genome Integrity;Developmental Genetics and Differentiation;Epigenetic Regulation and Gene Expression;and Human Genetics. A host of model genetic organisms are used in these areas. The program offers a comprehensive curriculum that provides a solid foundation in classical and modern molecular genetics. Following a series of laboratory rotations, students begin their PhD dissertation and engage in cutting-edge scientific inquiry. Training in scientific writing, oral presentation, and teaching is an integral part of the program. A career development series, exciting seminar series, student hosted speaker program, and annual scientific retreats provide opportunities for the students to gain experience as scientists, interact, and to develop to their maximum potential.
Genetics investigates the core principles of inheritance and adaption and as such represents a fundamental discipline in life sciences. To improve healthcare and to make advanced discoveries in medicine and biology, this program seeks to train the next generation of individuals with advanced knowledge and skills in the field of genetics and its related discipline of molecular biology.
|Parets, Sasha E; Bedient, Carrie E; Menon, Ramkumar et al. (2014) Preterm birth and its long-term effects: methylation to mechanisms. Biology (Basel) 3:498-513|
|Wiles 4th, Walter Guy; Mou, Zhongming; Du, Yang et al. (2014) Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality. In Vivo 28:709-18|
|Blanchard, Kristen; Robic, Srebrenka; Matsumura, Ichiro (2014) Transformable facultative thermophile Geobacillus stearothermophilus NUB3621 as a host strain for metabolic engineering. Appl Microbiol Biotechnol 98:6715-23|
|Van Bortle, Kevin; Nichols, Michael H; Li, Li et al. (2014) Insulator function and topological domain border strength scale with architectural protein occupancy. Genome Biol 15:R82|
|Lohsen, S; Majumder, P; Scharer, C D et al. (2014) Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types. Genes Immun 15:543-55|
|Wade, Brandy E; Wang, Chuan-En; Yan, Sen et al. (2014) Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissues. J Neurosci 34:8411-22|
|Pyhtila, Brook M; Shaw, Kelly A; Neumann, Samantha E et al. (2014) A brief overview of galactosemia newborn screening in the United States. J Inherit Metab Dis 37:649-50|
|Jumbo-Lucioni, Patricia P; Hopson, Marquise L; Hang, Darwin et al. (2013) Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia. Dis Model Mech 6:84-94|
|Wei, Han; Wang, Benlian; Miyagi, Masaru et al. (2013) PRMT5 dimethylates R30 of the p65 subunit to activate NF-*B. Proc Natl Acad Sci U S A 110:13516-21|
|Scharer, Christopher D; Barwick, Benjamin G; Youngblood, Benjamin A et al. (2013) Global DNA methylation remodeling accompanies CD8 T cell effector function. J Immunol 191:3419-29|
Showing the most recent 10 out of 34 publications