The goal of this T32 application is to support the continued training of surgical residents to become physician-scientists in Health Services and Translational Research. In our well-funded laboratories, the translational research training of surgical scientists will focus on the fields of trauma, burn, wound healing, and regenerative medicine while training will be initiated in the area of health services research in order to educate surgeons in the critical discipline of clinical outcomes investigation to promote evidenced-based medicine. The former emphasizes translating scientific discoveries from the research bench to the patient's bedside, whereas the latter centers on determining the efficacy of therapeutic interventions to improve clinical outcomes. The purpose of the health services research portion of the training grant is for young surgeons to integrate clinical experience with training in program development and research methods. The curriculum is designed to encourage the participants of the program to become future academic surgical investigators who will apply this training to find solutions to the many challenges posed by the U.S. healthcare system. The purpose of the translational scientific portion of the training grant is to provide formal instruction on laboratory research project design and sound research methods of hypothesis-driven investigation to push the boundaries of surgical innovation. The program will foster a cadre of well-prepared surgical scientists to ease their transition into academics. Future academic surgical investigators will benefit from greater knowledge in both important areas as they will be in the unique position to initiate research that bridges clinical and basic experimentation while also evaluating the effectiveness of their treatments. Our past trainees have successfully launched careers in academics and received PhDs using our T-32 grant training as a career defining experience. Through this newly structured organization in our next iteration of this training grant, this novel program is particularly well suited toward training th academic surgeons of the 21st century.

Public Health Relevance

For American surgical scientists to develop new therapies to treat patients with congenital and acquired wounds and deformities, and to determine the efficacy of those treatments, there is a fundamental need to train surgical investigators in these critical areas of medical care. This training grant brings together a successful and expert group of dedicated research investigators who will combine their efforts at a renowned university to train outstanding and promising surgical residents to develop new treatments to enhance healing and to determine the success of the surgical care that is delivered.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008616-17
Application #
9100757
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Somers, Scott D
Project Start
1997-09-01
Project End
2020-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
17
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Surgery
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Urlaub, Kevin M; Ettinger, Russell E; Nelson, Noah S et al. (2018) Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment. J Craniofac Surg :
Kumar, Nikit; Leonzino, Marianna; Hancock-Cerutti, William et al. (2018) VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J Cell Biol 217:3625-3639
Snider, Alicia E; Lynn, Jeremy V; Urlaub, Kevin M et al. (2018) Topical Deferoxamine Alleviates Skin Injury and Normalizes Atomic Force Microscopy Patterns Following Radiation in a Murine Breast Reconstruction Model. Ann Plast Surg 81:604-608
Harris, Chelsea A; Muller, John-Michael; Shauver, Melissa J et al. (2018) Leveraging the Medical Context to Increase Upper Extremity Reconstruction Among Patients With Tetraplegia: A Qualitative Analysis. Arch Phys Med Rehabil 99:459-467.e1
Frost, Christopher M; Ursu, Daniel C; Flattery, Shane M et al. (2018) Regenerative peripheral nerve interfaces for real-time, proportional control of a Neuroprosthetic hand. J Neuroeng Rehabil 15:108
Harris, Chelsea A; Muller, John-Michael; Shauver, Melissa J et al. (2017) Checkpoints to Progression: Qualitative Analysis of the Personal and Contextual Factors That Influence Selection of Upper Extremity Reconstruction Among Patients With Tetraplegia. J Hand Surg Am 42:495-505.e11
Hashmi, Asra; Khan, Faraz A; Herman, Floyd et al. (2017) A survey of current state of training of plastic surgery residents. BMC Res Notes 10:234
Harris, Chelsea A; Blencowe, Natalie; Telem, Dana A (2017) What is in a Pronoun?: Why Gender-fair Language Matters. Ann Surg 266:932-933
Carey, Edward G; Deshpande, Sagar S; Urlaub, Kevin M et al. (2017) Significant Differences in the Bone of an Isogenic Inbred Versus Nonisogenic Outbred Murine Mandible: A Study in Rigor and Reproducibility. J Craniofac Surg 28:915-919
Donneys, Alexis; Nelson, Noah S; Perosky, Joseph E et al. (2016) Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation. Bone 84:245-252

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