The UCSD Genetics Training Program (GTP) is designed to provide advanced training in Genetics and Genomics to predoctoral students beginning in their second graduate year. While several degree-granting programs at UCSD include genetics or genomics components, GTP is the sole point of integration across programs and builds both lateral and vertical cohorts of Ph.D. students interested in the history, practice and future applications of Genetics and Genomics in life and health sciences. Mentor laboratories encompass a broad range of basic science and clinical/translation research aims and span a range of organisms including microbial, plant, experimental animal and human subjects, but share a focus on genetic, epigenetic and genomic mechanisms and approaches. Students who have committed to thesis research in one of these laboratories can enter the training program and may be selected for support by this training grant. Students in the program take an advanced genetics curriculum that cuts across traditional graduate programs in several participating schools, division and departments at UCSD. Trainees take required graduate level courses in Genetics, Quantitative Methods, and participate in a weekly journal club attended in at least graduate years 2-4. The journal club includes rotating topics in contemporary genetics or classic, landmark papers relevant to the intellectual development of the field. Topics are selected by students, in consultation with participating faculty. A program-wide annual retreat, organized by year 5 students and a standing faculty committee, includes invited outside speakers, research presentations by program faculty and students. GTP has 33 students currently in training, for whom we are requesting 16 training grant slots.
The UCSD Genetics Training Program rigorously prepares an exceptional pool of students for professional careers in basic and applied research in life and health sciences. Our graduates have work in academic institutions, non-profit research institutions, biotechnology and drug research companies, and business firms that promote the development of health sciences companies.
|Panopoulos, Athanasia D; D'Antonio, Matteo; Benaglio, Paola et al. (2017) iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Stem Cell Reports 8:1086-1100|
|DeBoever, Christopher; Li, He; Jakubosky, David et al. (2017) Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells. Cell Stem Cell 20:533-546.e7|
|D Antonio, Matteo; Weghorn, Donate; D Antonio-Chronowska, Agnieszka et al. (2017) Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer. Nat Commun 8:436|
|Deffit, Sarah N; Yee, Brian A; Manning, Aidan C et al. (2017) The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis. Elife 6:|
|Searle, Naomi E; Torres-Machorro, Ana Lilia; Pillus, Lorraine (2017) Chromatin Regulation by the NuA4 Acetyltransferase Complex Is Mediated by Essential Interactions Between Enhancer of Polycomb (Epl1) and Esa1. Genetics 205:1125-1137|
|Valderrama, J Andrés; Riestra, Angelica M; Gao, Nina J et al. (2017) Group A streptococcal M protein activates the NLRP3 inflammasome. Nat Microbiol 2:1425-1434|
|Sharifnia, Panid; Kim, Kyung Won; Wu, Zilu et al. (2017) Distinct cis elements in the 3' UTR of the C. elegans cebp-1 mRNA mediate its regulation in neuronal development. Dev Biol 429:240-248|
|Carter, Hannah; Marty, Rachel; Hofree, Matan et al. (2017) Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer. Cancer Discov 7:410-423|
|Hammerling, Babette C; Najor, Rita H; Cortez, Melissa Q et al. (2017) A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun 8:14050|
|Corey, Victoria C; Lukens, Amanda K; Istvan, Eva S et al. (2016) A broad analysis of resistance development in the malaria parasite. Nat Commun 7:11901|
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