The UCSD Genetics Training Program (GTP) is designed to provide advanced training in Genetics and Genomics to predoctoral students beginning in their second graduate year. While several degree-granting programs at UCSD include genetics or genomics components, GTP is the sole point of integration across programs and builds both lateral and vertical cohorts of Ph.D. students interested in the history, practice and future applications of Genetics and Genomics in life and health sciences. Mentor laboratories encompass a broad range of basic science and clinical/translation research aims and span a range of organisms including microbial, plant, experimental animal and human subjects, but share a focus on genetic, epigenetic and genomic mechanisms and approaches. Students who have committed to thesis research in one of these laboratories can enter the training program and may be selected for support by this training grant. Students in the program take an advanced genetics curriculum that cuts across traditional graduate programs in several participating schools, division and departments at UCSD. Trainees take required graduate level courses in Genetics, Quantitative Methods, and participate in a weekly journal club attended in at least graduate years 2-4. The journal club includes rotating topics in contemporary genetics or classic, landmark papers relevant to the intellectual development of the field. Topics are selected by students, in consultation with participating faculty. A program-wide annual retreat, organized by year 5 students and a standing faculty committee, includes invited outside speakers, research presentations by program faculty and students. GTP has 33 students currently in training, for whom we are requesting 16 training grant slots.

Public Health Relevance

The UCSD Genetics Training Program rigorously prepares an exceptional pool of students for professional careers in basic and applied research in life and health sciences. Our graduates have work in academic institutions, non-profit research institutions, biotechnology and drug research companies, and business firms that promote the development of health sciences companies.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008666-16
Application #
8697056
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Haynes, Susan R
Project Start
1998-07-01
Project End
2017-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Benthuysen, Jacqueline R; Carrano, Andrea C; Sander, Maike (2016) Advances in β cell replacement and regeneration strategies for treating diabetes. J Clin Invest 126:3651-3660
Batra, Ranjan; Stark, Thomas J; Clark, Elizabeth et al. (2016) RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nat Struct Mol Biol 23:1101-1110
Martinez, Fernando J; Pratt, Gabriel A; Van Nostrand, Eric L et al. (2016) Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. Neuron 92:780-795
Brannan, Kristopher W; Jin, Wenhao; Huelga, Stephanie C et al. (2016) SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes. Mol Cell 64:282-293
Schoeller, Erica L; Clark, Daniel D; Dey, Sandeepa et al. (2016) Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. Endocrinology 157:4914-4929
Brandler, William M; Antaki, Danny; Gujral, Madhusudan et al. (2016) Frequency and Complexity of De Novo Structural Mutation in Autism. Am J Hum Genet 98:667-79
Conway, Anne E; Van Nostrand, Eric L; Pratt, Gabriel A et al. (2016) Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep 15:666-79
Corey, Victoria C; Lukens, Amanda K; Istvan, Eva S et al. (2016) A broad analysis of resistance development in the malaria parasite. Nat Commun 7:11901
Kapeli, Katannya; Pratt, Gabriel A; Vu, Anthony Q et al. (2016) Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun 7:12143
Szumowski, Suzannah C; Estes, Kathleen A; Popovich, John J et al. (2016) Small GTPases promote actin coat formation on microsporidian pathogens traversing the apical membrane of Caenorhabditis elegans intestinal cells. Cell Microbiol 18:30-45

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