Support is requested to continue a multidisciplinary predoctoral training program in Molecular and Cellular Biology at Dartmouth. The trainees and trainers in the "Molecular and Cellular Biology at Dartmouth" Training Program (MCBD) are selected from Dartmouth's largest and most diverse life science graduate program, the Molecular and Cellular Biology (MCB) graduate program. The MCB graduate program is an interdepartmental, interdisciplinary program with 155 students that spans nine different academic departments at Dartmouth College, Dartmouth Medical School, and the Thayer School of Engineering. The MCB graduate program regularly matriculates 25-30 students per year who are selected from highly qualified national and international pools of applicants that are rich in both ethnic and racial diversity. Eight predoctoral trainees for the MCBD Training Program are selected for two years of support based upon their academic qualifications and must satisfy the diverse and rigorous MCB graduate program curriculum that includes a three-term core course, three 10-week research rotations, three elective courses, one term of teaching, participation in journal clubs and seminars, training in responsible conduct of research, a written and oral qualifying exam, a yearly Research in Progress seminar, and the completion of a significant research project that forms the foundation of a written thesis that is orally defended. Faculty in the MCBD Training Program include 48 extramurally funded faculty who are elected based on the strength of their research programs and their demonstrated commitment to participating in the activities necessary for effective predoctoral training. The research areas of the faculty are broad and interdisciplinary to support the development of the trainees and include bioinformatics, cell biology, developmental biology, immunology, molecular pathogenesis, neurobiology, gene expression, signal transduction, cellular metabolism, proteomics, and structural biology. It is through the dedication and expertise of the faculty and the rigorous curriculum that the MCBD Training Program reaches the goal of recruiting and training the next generation of outstanding young scientists for productive careers in the biomedical sciences.

Public Health Relevance

This proposal seeks funds to continue a multidisciplinary predoctoral training program in Molecular and Cellular Biology at Dartmouth. The goals of this training program are to recruit and train outstanding graduate students and to prepare them for productive careers in science. Training the next generation of scientists is essential for maintaining and improving the economy of our country and the health of its citizens. This training program will support young scientists during their training that strives to prepare them for productive careers as researchers and teachers in the biomedical sciences.

National Institute of Health (NIH)
Institutional National Research Service Award (T32)
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National Institute of General Medical Sciences Initial Review Group (BRT)
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Gindhart, Joseph G
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Dartmouth College
Schools of Medicine
United States
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Kuchma, S L; Delalez, N J; Filkins, L M et al. (2015) Cyclic di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa PA14 requires the MotAB stator. J Bacteriol 197:420-30
Bridges, Andrew A; Gladfelter, Amy S (2014) Fungal pathogens are platforms for discovering novel and conserved septin properties. Curr Opin Microbiol 20:42-8
Deng, Lin; Kabeche, Ruth; Wang, Ning et al. (2014) Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1. Mol Biol Cell 25:2660-8
Kabeche, Ruth; Roguev, Assen; Krogan, Nevan J et al. (2014) A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation. J Cell Sci 127:1318-26
Roy, Sarah H; Tobin, David V; Memar, Nadin et al. (2014) A complex regulatory network coordinating cell cycles during C. elegans development is revealed by a genome-wide RNAi screen. G3 (Bethesda) 4:795-804
Ballok, Alicia E; Filkins, Laura M; Bomberger, Jennifer M et al. (2014) Epoxide-mediated differential packaging of Cif and other virulence factors into outer membrane vesicles. J Bacteriol 196:3633-42
Hatch, Anna L; Gurel, Pinar S; Higgs, Henry N (2014) Novel roles for actin in mitochondrial fission. J Cell Sci 127:4549-60
Guo, Bingqian; Gurel, Pinar S; Shu, Rui et al. (2014) Monitoring ATP hydrolysis and ATPase inhibitor screening using (1)H NMR. Chem Commun (Camb) 50:12037-9
George, Carolyn M; Bozler, Julianna; Nguyen, Huy Q et al. (2014) Condensins are Required for Maintenance of Nuclear Architecture. Cells 3:865-82
Amacher, Jeanine F; Cushing, Patrick R; Brooks 3rd, Lionel et al. (2014) Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses. Structure 22:82-93

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