The mission of the training program in Cellular and Molecular Medicine is to prepare PhD scientists for laboratory research at the cellular and molecular level on topics with a direct impact on the understanding, diagnosis, treatment and prevention of human diseases. Through a series of tailored courses, small group discussions, clinical Grand Rounds and laboratory research, PhD graduates of this program are provided a rigorous training in scientific research and a thorough knowledge of human biology and human diseases. Consistent with the emphasis on translational research, most CMM faculty work in clinical settings, distributed over 23 clinical and basic science departments and 4 institutes within the Johns Hopkins School of Medicine and School of Public Health. Trainers are rigorously evaluated according to criteria of merit, mentorship ability and program fit, and the faculty: student ratio of 1 is maintained by an active process of mentor recruitment, renewal and turnover to ensure the best training environment for our PhD candidates. The first year curriculum begins with the intensive Introduction to Human Body course that combines hands-on dissection of the human cadaver, virtual histology labs, in-class and e-lectures, and small group presentations by students. Following a rigorous curriculum in principles in molecular biology, genetics, biochemistry and cell biology, accompanied by three 10-week laboratory rotations, the year ends with Cellular and Molecular Basis of Disease that covers a spectrum of clinically and/or socially relevant disorders of the human body, also arranged by organ systems, completing the cycle of the year from book to bench to bedside. Other program- specific activities include a practical Grant Writing course and clinical Grand Rounds in the second year. The program sponsors an Annual Retreat and career training opportunities in teaching and non-academic tracks. Most trainees graduate pursue research careers in academia (43%), medicine (15%) or industry (27%). Currently in its 20th year, CMM supports trainees in their first year of graduate training. In this renewal, funds are requested 2 additiona training slots for a total of 17, to accommodate increased applications from an outstanding pool of training grant eligible candidates, including underrepresented groups.

Public Health Relevance

The graduate program in Cellular and Molecular Medicine prepares PhD scientists by rigorous course work and laboratory training in translational research with direct relevance to the understanding and treatment of human disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM008752-17S2
Application #
9275774
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Cole, Alison E
Project Start
2000-07-01
Project End
2020-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
17
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Physiology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Vermillion, Meghan S; Klein, Sabra L (2018) Pregnancy and infection: using disease pathogenesis to inform vaccine strategy. NPJ Vaccines 3:6
Liu, Rui Han; Ong, Chin Siang; Fukunishi, Takuma et al. (2018) Review of Vascular Graft Studies in Large Animal Models. Tissue Eng Part B Rev 24:133-143
Amend, Sarah R; de Groot, Amber E; Torga, Gonzalo et al. (2018) Ten unanswered questions in cancer: ""If this is true, what does it imply""? Am J Clin Exp Urol 6:26-31
Ong, Chin Siang; Nam, Lucy; Ong, Kingsfield et al. (2018) 3D and 4D Bioprinting of the Myocardium: Current Approaches, Challenges, and Future Prospects. Biomed Res Int 2018:6497242
Cravero, Karen; Medford, Arielle; Pallavajjala, Aparna et al. (2018) Biotinylated amplicon sequencing: A method for preserving DNA samples of limited quantity. Pract Lab Med 12:e00108
Barrington, William T; Wulfridge, Phillip; Wells, Ann E et al. (2018) Improving Metabolic Health Through Precision Dietetics in Mice. Genetics 208:399-417
Vermillion, Meghan S; Nelson, Andrew; Vom Steeg, Landon et al. (2018) Pregnancy preserves pulmonary function following influenza virus infection in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol 315:L517-L525
Porter, Corey M; Shrestha, Eva; Peiffer, Lauren B et al. (2018) The microbiome in prostate inflammation and prostate cancer. Prostate Cancer Prostatic Dis 21:345-354
Bettridge, Kelsey E; Cook, Ashley L; Ziegelstein, Roy C et al. (2018) A Scientist's Oath. Mol Cell 71:879-881
El-Diwany, Ramy; Soliman, Mary; Sugawara, Sho et al. (2018) CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans. Sci Adv 4:eaat0843

Showing the most recent 10 out of 274 publications