Biostatistics plays a fundamental role in medical, biomedical and public health research. Advances in medical technology alone have substantially increased the demand for trained biostatisticians to demonstrate basic scientific knowledge, effectiveness and feasibility. There is a growing need for biostatisticians to be trained in a broad range of fields, including the biological sciences, quantitative sciences and clinical applications. Researchers in the medical and life sciences are expressing a growing need for applied biostatisticians who are trained with a background in biology and strong communication skills as well as quantitative skills. Most applied biostatisticians function in collaborative environments that require interdisciplinary knowledge and strong communication skills, but many do not receive training in biology and bioinformatics. Not only do biostatisticians need to be trained how to apply the wide range of quantitative methods that are needed in biomedical research, but they also need an understanding of the biological basis for disease and the biological measures that are collected in biomedical research. The goal of this training grant proposal is to seek continued funding for our training program for pre-doctoral students in biostatistics that provides a strong background in quantitative skills, biology, applied research and exposure to the proper conduct of ethical research. Our program of 1-3 years includes course work required of all biostatistics doctoral students along with rotations in bioinformatics, genetics, ethical conduct of research, observational studies and clinical trials. In the rotations students work on an applied research project gaining important experience in an environment that provides excellent experience in interdisciplinary research. This program produces students not only with classroom exposure to quantitative skills, but also practical experience as a functioning biostatistician.

Public Health Relevance

The NIH has identified a growing need to educate biostatisticians through an interdisciplinary approach. Additionally, there is a growing need to include minorities and disabled persons in this important field. This program plays an important role in addressing both needs within the United States.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM074905-09
Application #
8503611
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Brazhnik, Paul
Project Start
2005-07-01
Project End
2015-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
9
Fiscal Year
2013
Total Cost
$223,273
Indirect Cost
$10,613
Name
Boston University
Department
Biostatistics & Other Math Sci
Type
Schools of Public Health
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
McCabe, Elizabeth L; Larson, Martin G; Lunetta, Kathryn L et al. (2016) Association of an Index of Healthy Aging With Incident Cardiovascular Disease and Mortality in a Community-Based Sample of Older Adults. J Gerontol A Biol Sci Med Sci 71:1695-1701
Sebastiani, Paola; Andersen, Stacy L; McIntosh, Avery I et al. (2016) Familial Risk for Exceptional Longevity. N Am Actuar J 20:57-64
Pers, Tune H; Timshel, Pascal; Ripke, Stephan et al. (2016) Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes. Hum Mol Genet 25:1247-54
Bae, Harold; Monti, Stefano; Montano, Monty et al. (2016) Learning Bayesian Networks from Correlated Data. Sci Rep 6:25156
Lent, Samantha; Deng, Xuan; Cupples, L Adrienne et al. (2016) Imputing rare variants in families using a two-stage approach. BMC Proc 10:209-214
Vathipadiekal, Vinod; Alsultan, Abdulrahman; Baltrusaitis, Kristin et al. (2016) Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol 91:E308-11
Vathipadiekal, Vinod; Farrell, John J; Wang, Shuai et al. (2016) A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol 91:1118-1122
Vardi, M; Cryer, B L; Cohen, M et al. (2015) The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. Aliment Pharmacol Ther 42:365-74
Sun, Fangui; Sebastiani, Paola; Schupf, Nicole et al. (2015) Extended maternal age at birth of last child and women's longevity in the Long Life Family Study. Menopause 22:26-31
Sebastiani, P; Farrell, J J; Alsultan, A et al. (2015) BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis 54:224-30

Showing the most recent 10 out of 23 publications