The MD-PhD Program at the. Medical College of Wisconsin (MCW) provides outstanding clinical and research training as an educational foundation for academic physician scientists of the future. MCW is the third largest private medical school in the country and is one of the fastest growing medical schools in terms of research funding. The Graduate School awards the PhD degree in biochemistry, biophysics, biostatistics, cell and developmental biology, neurobiology, microbiology and molecular genetics, pharmacology, physiology, and functional imaging. MCW has fully supported the MD-PhD degree program since 1982. Trainees receive a stipend and full tuition wavier during all years of graduate and medical studies. The current administrators in the MD-PhD Program have a combined 26 years of service in leadership positions. Trainees pursue the combined degrees following either a Traditional (2-4-2) - or Integrated- Track. There are currently 31 trainees in the Program. Trainees participate in a myriad of activities including a monthly Research in Progress, a Luncheon series with Invited Physician Scientists, an annual Retreat, a Visiting Professor Lecture, and an Alumni Seminar. Trainees obtain teaching experiences through MSTP Integrated Grand Rounds presented to all first and second year medical students. In addition, 9 students have been asked to tutor medical students. Seventy-nine percent of our Program graduates are full time residents, fellows, or faculty at academic institutions;six with faculty status have secured external funding as a Principal Investigator. Nine of our 19 current trainees (47%) have successfully competed for independent fellowships during their graduate school years. The Program is committed to diversity among trainees. MCW research has grown through research centers, which provide trainees a breadth of research opportunities. Center-driven research also provides trainees an opportunity to conduct basic, mechanistic research in a collaborative and translational environment. Each trainee's program is individualized to fit their career interests. MCW seeks support from the NIGMS to expand the existing Program to align with the growth of MCW's research efforts to expand the incoming class from 4 to 6 trainees.

Public Health Relevance

(See Instructions): Relevance: There is a shortage of Physician Scientists who conduct research in the basic sciences and also have academic careers in medicine. This training grant will support the basic research and medical training of students who are seeking the dual MD/PhD degree to become Physician Scientists.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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National Institute of General Medical Sciences Initial Review Group (BRT)
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Preusch, Peter C
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Medical College of Wisconsin
Schools of Medicine
United States
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Zimmerman, Noah P; Roy, Ishan; Hauser, Andrew D et al. (2015) Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells. Mol Carcinog 54:203-15
Scoles, Drew; Sulai, Yusufu N; Langlo, Christopher S et al. (2014) In vivo imaging of human cone photoreceptor inner segments. Invest Ophthalmol Vis Sci 55:4244-51
Roy, Ishan; Veldkamp, Christopher T; Volkman, Brian F et al. (2014) Chemokines in colitis: microRNA control. Gut 63:1202-4
Sundaram, Venki; Wilde, Caroline; Aboshiha, Jonathan et al. (2014) Retinal structure and function in achromatopsia: implications for gene therapy. Ophthalmology 121:234-45
Roberts, Christopher J; Stuhr, Kara L; Hutz, Michael J et al. (2014) Endocannabinoid signaling in hypothalamic-pituitary-adrenocortical axis recovery following stress: effects of indirect agonists and comparison of male and female mice. Pharmacol Biochem Behav 117:17-24
Johar, Kaid; Priya, Anusha; Wong-Riley, Margaret T T (2014) Regulation of Na(+)/K(+)-ATPase by neuron-specific transcription factor Sp4: implication in the tight coupling of energy production, neuronal activity and energy consumption in neurons. Eur J Neurosci 39:566-78
Prisco, Anthony R; Bukowy, John D; Hoffmann, Brian R et al. (2014) Automated quantification reveals hyperglycemia inhibits endothelial angiogenic function. PLoS One 9:e94599
Prisco, Sasha Z; Prokop, Jeremy W; Sarkis, Allison B et al. (2014) Refined mapping of a hypertension susceptibility locus on rat chromosome 12. Hypertension 64:883-90
Priya, Anusha; Johar, Kaid; Nair, Bindu et al. (2014) Specificity protein 4 (Sp4) regulates the transcription of AMPA receptor subunit GluA2 (Gria2). Biochim Biophys Acta 1843:1196-206
Kropp, Erin M; Bhattacharya, Subarna; Waas, Matthew et al. (2014) N-glycoprotein surfaceomes of four developmentally distinct mouse cell types. Proteomics Clin Appl 8:603-9

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