The training program, open to physicians (MD or MD/PhD)during their residency training or as a post- graduate research fellowship and to basic scientists (PhD) early in their research career, is designed to provide 2 years of research training in perioperative science. The major goal of this training program is to provide the highest caliber research training in four Specific Themes originating from existing strengths of our faculty at Vanderbilt University Medical Center. The Research Themes include: 1) Mechanisms and Management of Pain;2) Perioperative Stress Biology and Outcomes;3) Perioperative Health Services and Translational Research;and 4) Personalized Medicine and Pharmacogenomics. Each of these themes directly relates to the overarching aim of the program - to train the next generation of scientists to create new knowledge and translate it into best evidence for personalized perioperative care and pain management at a population level. The training faculty will consist of an exceptionally strong collection of physician-scientists and basic scientists who offer superb interdisciplinary research training opportunities in 7 different academic departments. The training program will accept three new trainees per year (maximum 6 participants per year) with ratios depending on availability: 4 clinicians and 2 PhDs or 3 clinicians and 3 Ph.Ds. Clinicians who show exceptional aptitude for successfully pursuing an academic research career and Ph.D. scientists who demonstrate the best aptitude to develop towards independence will be considered for participation. Each participant will commit to a 2 year basic science, clinical and/or translational research project with 75% effort for Clinicians and 100% effort for PhDs. In addition to their research project training, trainees will receive coursework instruction in research related processes such grant writing, publications, ethics, and responsible conduct of research. This training will prepare them to utilize the skills they acquire in the pursuit of future academic research careers.

Public Health Relevance

This training program in basic, clinical, and translational research will train basic and physician scientists in mechanisms and management of pain, perioperative stress biology and outcomes, health service and translational research, and personalized medicine and pharmacogenomics. The program will prepare future researchers for the unique challenges associated with the optimization of perioperative care.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
1T32GM108554-01
Application #
8607868
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Cole, Alison E
Project Start
2014-07-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37212
Hubers, Scott A; Brown, Nancy J (2016) Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition. Circulation 133:1115-24
O'Neal, Jason B; Shaw, Andrew D (2016) Predicting, preventing, and identifying delirium after cardiac surgery. Perioper Med (Lond) 5:7
O'Neal, Jason B; Shaw, Andrew D; Billings 4th, Frederic T (2016) Acute kidney injury following cardiac surgery: current understanding and future directions. Crit Care 20:187
Currier, Michael G; Lee, Sujin; Stobart, Christopher C et al. (2016) EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression. PLoS Pathog 12:e1005622
Spampinato, M V; Langdon, B R; Patrick, K E et al. (2016) Gender, apolipoprotein E genotype, and mesial temporal atrophy: 2-year follow-up in patients with stable mild cognitive impairment and with progression from mild cognitive impairment to Alzheimer's disease. Neuroradiology :
Hubers, Scott A; Brown, Nancy J (2016) Response by Hubers and Brown to Letter Regarding Article, ""Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition"". Circulation 134:e11-2
O'Neal, Jason B; Shaw, Andrew D (2016) Goal-directed therapy in the operating room: is there any benefit? Curr Opin Anaesthesiol 29:80-4
Efird, Jimmy T; Gudimella, Preeti; O'Neal, Wesley T et al. (2016) Comparison of Risk of Atrial Fibrillation in Black Versus White Patients After Coronary Artery Bypass Grafting. Am J Cardiol 117:1095-100
Parker, Ryan O; King, Adam B; Hughes, Christopher G (2016) Dexmedetomidine for the treatment of hyperactive delirium refractory to haloperidol in non-intubated patients. J Thorac Dis 8:E596-8
Nguyen, Thanh T; Lam, Humphrey V; Phillips, Maxie et al. (2015) Intraoperative optimization to decrease postoperative PRBC transfusion in children undergoing craniofacial reconstruction. Paediatr Anaesth 25:294-300

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