The goal of this postdoctoral training program, since its inception in 1977, has been to provide physicians interested in perinatal/neonatal medicine the skills necessary for a successful career in academic medicine. There are many excellent clinical training programs in perinatal/neonatal medicine in the United States, but few provide intensive training in laboratory, translational, and clinical research. As a result, there are many well- trained clinicians, but relatively few equipped for research-oriented academic positions. Physician-investigators bring a unique perspective to biomedical research and its translation. In this program, physician trainees pursue intensive training and investigation in one of two tracks. One track is a traditional laboratory-based track that focuses on molecular, cellular, and developmental biology. Trainees in this track are mentored in the laboratories of senior investigators in the Yale School of Medicine. The other track focuses on clinical and translational investigation. Trainees in this track are mentored by senior investigators in the Yale School of Medicine and/or the Yale School of Public Health. Formal didactic training is offered to trainees in both tracks and all trainees are required to attend instruction in biostatistics, evidence based medicine, clinical trial design, epidemiology, and ethical conduct of research. Trainees who elect to do clinical research may also become candidates for the MPH degree at the Yale School of Public Health or the PhD in Investigative Medicine. The program supports 4 postdoctoral trainees. Trainees are appointed for 3 years and must be committed to pursuing a career in academic medicine. MD trainees will have completed their residency prior to entering the program. After an orientation period, with guidance from the program directors and an advisory committee, trainees select a preceptor and a research project. Under the direct supervision of the preceptor, they design, execute, interpret and report their research. Since 3 years are generally insufficient to fully establish an independent research career, trainees are encouraged and assisted to apply for funding to extend their research training, and many have done so successfully. In depth tools for trainee, preceptor, and training program evaluation are in place, as are tools for trainee recruitment, particularly for recruitment of trainees from diverse backgrounds. The training program is significantly enhanced by the resources and environment of Yale University, a research-intensive institution. Numerous research and training opportunities exist, particularly in the Schools of Medicine and Public Health, which provide a rich environment for training in biomedical research. The approach of using the resources of Yale University for training in academic medicine has been rewarding in terms of trainee productivity and subsequent career development. Graduates of this program hold academic positions throughout the United States. Many have become leaders in perinatal/neonatal medicine and research. The ongoing objective of this program is to train members of the next generation of investigators in perinatal/neonatal medicine.

Public Health Relevance

This proposal supports postdoctoral training in Perinatal Medicine in the Department of Pediatrics, Yale University School of Medicine. In place for over thirty years, this training program has successfully placed many graduates into positions in academic pediatrics. Continuing this tradition, the long-term goal of this proposal is to foster the career development of physician investigators in basic science, translational, and clinical research. A program with considerable depth and expertise in many areas of biomedical research and research training is in place. Fellows participate in a rigorous curriculum of training that includes formal coursework, hands on experience, and careful mentoring.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD007094-37
Application #
8474796
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Raju, Tonse N
Project Start
1977-07-04
Project End
2016-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
37
Fiscal Year
2013
Total Cost
$265,113
Indirect Cost
$18,305
Name
Yale University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Scheinost, Dustin; Kwon, Soo Hyun; Lacadie, Cheryl et al. (2016) Prenatal stress alters amygdala functional connectivity in preterm neonates. Neuroimage Clin 12:381-8
Kwon, Soo Hyun; Scheinost, Dustin; Vohr, Betty et al. (2016) Functional magnetic resonance connectivity studies in infants born preterm: suggestions of proximate and long-lasting changes in language organization. Dev Med Child Neurol 58 Suppl 4:28-34
Eicher, John D; Montgomery, Angela M; Akshoomoff, Natacha et al. (2016) Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Brain Imaging Behav 10:272-82
Malhotra, Yogangi; Nzegwu, Nneka; Harrington, Jamie et al. (2016) Identifying Barriers to Initiating Minimal Enteral Feedings in Very Low-Birth-Weight Infants: A Mixed Methods Approach. Am J Perinatol 33:47-56
Truong, D T; Shriberg, L D; Smith, S D et al. (2016) Multipoint genome-wide linkage scan for nonword repetition in a multigenerational family further supports chromosome 13q as a locus for verbal trait disorders. Hum Genet 135:1329-1341
Scheinost, Dustin; Kwon, Soo Hyun; Shen, Xilin et al. (2016) Preterm birth alters neonatal, functional rich club organization. Brain Struct Funct 221:3211-22
Laursen, Willem J; Schneider, Eve R; Merriman, Dana K et al. (2016) Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels. Proc Natl Acad Sci U S A 113:11342-11347
Levit, Orly L; Calkins, Kara L; Gibson, L Caroline et al. (2016) Low-Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates. JPEN J Parenter Enteral Nutr 40:374-82
Schneider, Eve R; Gracheva, Elena O; Bagriantsev, Slav N (2016) Evolutionary Specialization of Tactile Perception in Vertebrates. Physiology (Bethesda) 31:193-200
Kwon, Soo Hyun; Scheinost, Dustin; Lacadie, Cheryl et al. (2015) Adaptive mechanisms of developing brain: cerebral lateralization in the prematurely-born. Neuroimage 108:144-50

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