The Center for Clinical Epidemiology and Biostatistics (CCEB) and the Department of Obstetrics and Gynecology of the University of Pennsylvania School of Medicine, collaborating with the Division of Neonatology, Department of Pediatrics of the Children's Hospital of Philadelphia, apply to continue an innovative and successful post-doctoral training program in reproductive epidemiology for individuals who already are physicians. Penn and the School of Medicine promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for trainees. This training program attracts reproductive epidemiology trainees from other institutions nationwide and the graduates of this training program are placed in other institutions nationwide, resulting in a program of the highest impact. The two- to three-year training program consists of required courses in clinical epidemiology, research methodology, biostatistics, and reproductive epidemiology;elective courses;journal clubs and clinical research conferences focusing on research issues in reproductive medicine, women's health, and/or neonatology;extensive independent readings;attendance at and participation in research seminars at the CCEB, the Department of Obstetrics and Gynecology, and the Division of Neonatology;and the completion of an independent research project in reproductive epidemiology. The program is designed to: 1) train clinicians to be rigorous and independent academic investigators able to use the range of approaches available in epidemiology to address research issues in reproductive medicine, women's health, and/or neonatology related to the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care;2) provide closely mentored research experiences with faculty preceptors in clinical epidemiology, obstetrics and gynecology, and neonatology;and 3) strengthen the links between traditional epidemiology, obstetrics and gynecology, neonatology, and women's health. Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) degree program. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB, the Department of Obstetrics and Gynecology, and the Division of Neonatology;2) the collaborative links that have been forged among the faculty of these academic entities;3) the comprehensive course offerings and research programs that are available to trainees;and 4) an extensive set of experienced program directors and faculty preceptors with successful training records. In addition, the availability of the broad range of rich expertise of the faculties in the CCEB, the Department of Obstetrics and Gynecology, and the Division of Neonatology;numerous existing large databases that can be used for research projects and training;a broad array of specialized analytic capabilities available for clinical studies (e.g., clinical trials, case-control, cohort research, etc.);and the faculties'commitment to collaborative research and training, combine to provide an ideal environment for this training program.

Public Health Relevance

There is a major national shortage of qualified clinicians able to conduct rigorous clinical research in reproductive epidemiology. This training program addresses this shortage through the collaborative efforts of reproductive epidemiologists, obstetricians, gynecologists, and neonatologists. Specific research areas of focus of mentors and trainees include: fetal origins of adult disease, contribution of maternal illness to adverse perinatal and childhood outcomes, adverse childhood outcomes associated with assisted reproductive technologies, and the association of the transition into menopause and urogynecologic disorders.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD007440-19
Application #
8659193
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Parrott, Estella C
Project Start
1996-05-01
Project End
2016-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
19
Fiscal Year
2014
Total Cost
$352,619
Indirect Cost
$24,453
Name
University of Pennsylvania
Department
Biostatistics & Other Math Sci
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Chan, Jessica L; Letourneau, Joseph; Salem, Wael et al. (2016) Regret around fertility choices is decreased with pre-treatment counseling in gynecologic cancer patients. J Cancer Surviv :
Chandrasekaran, Suchitra; Bastek, Jamie A; Turitz, Amy L et al. (2016) A prediction score to assess the risk of delivering a large for gestational age infant among obese women. J Matern Fetal Neonatal Med 29:22-6
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Haggerty, Ashley F; Huepenbecker, Sarah; Sarwer, David B et al. (2016) The use of novel technology-based weight loss interventions for obese women with endometrial hyperplasia and cancer. Gynecol Oncol 140:239-44
Chan, Jessica L; Letourneau, Joseph; Salem, Wael et al. (2015) Sexual satisfaction and quality of life in survivors of localized cervical and ovarian cancers following fertility-sparing surgery. Gynecol Oncol 139:141-7
Chandrasekaran, Suchitra; Levine, Lisa D; Durnwald, Celeste P et al. (2015) Excessive weight gain and hypertensive disorders of pregnancy in the obese patient. J Matern Fetal Neonatal Med 28:964-8
Levine, Lisa D; Sammel, Mary D; Hirshberg, Adi et al. (2015) Does stage of labor at time of cesarean delivery affect risk of subsequent preterm birth? Am J Obstet Gynecol 212:360.e1-7
Levine, Lisa D; Limaye, Meghana; Srinivas, Sindhu K (2015) The utility of ICD9-CM codes in identifying induction of labor. Am J Perinatol 32:475-80
Chan, Jessica L; Johnson, Lauren N C; Efymow, Brenda L et al. (2015) Outcomes of ovarian stimulation after treatment with chemotherapy. J Assist Reprod Genet 32:1537-45

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