The objective of this proposal is to train predoctoral students in Developmental Biology. Thirty-five faculty propose continuation of a broad, interdisciplinarytraining program. These faculty use molecular, cellbiological and genetic approaches to address fundamental problems in developmental biology. Participating faculty have appointments in a total of 14 basic science and clinical departments within the university. All have extremely active research programs. Productive interactions between laboratories and trainees are promoted by an annual retreat, symposium/journal club series, joint research meetings, shared supervision, and a variety of collaborations. The program is conducted within the broader context of the Program in Biological Sciences, a consortium of eight UCSF graduate programs with more than 100 participatingfaculty. It attracts students of exceptionally high caliber. The features of our training program that are especially attractive to prospective students are the following: (1) a wide choice of laboratories for thesis research, (2) a laboratory rotation system, (3) an excellent set of courses, (4) a tutorial in how to present a seminar, (5) a highly cooperative spirit, and (6) an awareness that graduate training is important to the faculty at UCSF. We strive to facilitate the intellectual growth and scientific skills of each trainee so that each graduates as an independentscientist who will be able to contribute to the field for many decades to come.
Training the next generation of developmental biologists is essential for gaining an understanding of the fundamental mechanisms of embryonic development, which is one of the most expeditious routes to discovering therapies for many human diseases.
|Kimmel, Jacob C; Chang, Amy Y; Brack, Andrew S et al. (2018) Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance. PLoS Comput Biol 14:e1005927|
|Yang, Xiao Yong; Stanley, Robert E; Ross, Adam P et al. (2018) Sestd1 Encodes a Developmentally Dynamic Synapse Protein That Complexes With BCR Rac1-GAP to Regulate Forebrain Dendrite, Spine and Synapse Formation. Cereb Cortex :|
|Andersen, Rebecca E; Lim, Daniel A (2018) Forging our understanding of lncRNAs in the brain. Cell Tissue Res 371:55-71|
|Pla, Ramon; Stanco, Amelia; Howard, MacKenzie A et al. (2018) Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis. Cereb Cortex 28:3797-3815|
|Woronowicz, Katherine C; Gline, Stephanie E; Herfat, Safa T et al. (2018) FGF and TGF? signaling link form and function during jaw development and evolution. Dev Biol :|
|Freimer, Jacob W; Krishnakumar, Raga; Cook, Matthew S et al. (2018) Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes. Curr Biol 28:296-302.e3|
|Smith, Lucas K; White 3rd, Charles W; Villeda, Saul A (2018) The systemic environment: at the interface of aging and adult neurogenesis. Cell Tissue Res 371:105-113|
|Altshuler-Keylin, Svetlana; Kajimura, Shingo (2017) Mitochondrial homeostasis in adipose tissue remodeling. Sci Signal 10:|
|Susman, Michael W; Karuna, Edith P; Kunz, Ryan C et al. (2017) Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. Elife 6:|
|Hérault, Aurélie; Binnewies, Mikhail; Leong, Stephanie et al. (2017) Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature 544:53-58|
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