The Pediatric Emergency Medicine Research Training Program (PEMRTP), established in 2001, offers unique multi-disciplinary training for MD and PhD biomedical researchers to acquire necessary skills for investigating the acute illnesses and injuries that form the clinical basis of the subspecialty of pediatric emergency medicine. In the United States, between 19 and 25 million children make more than 29 million emergency department (ED) visits each year. Eighteen percent of children have at least one ED visit annually. About 4% of these visits result in hospitalizations. The total annual cost of ED care is almost $50 billion and 20% of visits are for children. When arriving at the ED, a parent can think of nothing more important than that their acutely ill or injured child receive the best, evidence-based care with the most effective diagnostics and treatments. Pediatric research makes this possible. The NIH recognizes the importance of emergency medicine research and has recently designated a trans-NIH Office of Emergency Care Research to foster basic, translational, and clinical research and training for the emergency setting. This T32 competing renewal leverages the assets of Boston Children?s Hospital Emergency Department, which includes the largest pediatric emergency medicine faculty, and leading informatics programs at Harvard. PEMRTP draws on core strengths to create a culture of rigorous research and research training to (1) prepare individual trainees as independent researchers, (2) fill the critical need for early and mid-career research mentors for the next generation of pediatric emergency medicine trainees here and elsewhere, and (3) bolster pediatric emergency medicine research with biomedical informatics and genomics. Trainees progress toward independence in three interrelated phases: (1) a mentored research project, (2) formal course work, and (3) preparation of a research grant. Trainees complete either a Master of Medical Science or Master of Public Health degree. They are mentored in their laboratory of choice. And finally, with guidance from a faculty mentor, they prepare a K99/R00 or similar mentored research grant application to facilitate their transition to independent faculty. Boston Children?s Hospital and Harvard Medical School, by the breadth and depth of their research laboratories, operational, real-world clinical systems, formal academic programs, experienced faculty, and linkages to multisite research networks, provide an unparalleled environment for mentoring trainees to become future leaders. PEMRTP specifically builds on the international reputation of Boston Children?s Hospital in biomedical informatics and genomics and seeks to train its fellows to use tools from these fields to exploit the pediatric ED as a laboratory for clinical, translational and population research.

Public Health Relevance

In the United States, 19 to 25 million children make more than 29 million emergency department (ED) visits each year. The Pediatric Emergency Medicine Training Program offers unique training in biomedical informatics and genomics for the next generation of leaders in pediatric acute care research. Thus, when ill or injured children arrive at the ED, they can receive the best evidence-based care, with the most effective diagnostics and treatments possible.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
2T32HD040128-16
Application #
9702440
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Maholmes, Valerie
Project Start
2001-05-15
Project End
2024-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
16
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Boston Children's Hospital
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Kantor, David B; Petty, Carter R; Phipatanakul, Wanda et al. (2018) Transcutaneous CO-oximetry differentiates asthma exacerbation and convalescence in children. J Allergy Clin Immunol 142:676-678.e5
Cruz, Andrea T; Freedman, Stephen B; Kulik, Dina M et al. (2018) Herpes Simplex Virus Infection in Infants Undergoing Meningitis Evaluation. Pediatrics 141:
O'Reilly, Kathleen M; Lowe, Rachel; Edmunds, W John et al. (2018) Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis. BMC Med 16:180
Leta, Samson; Beyene, Tariku Jibat; De Clercq, Eva M et al. (2018) Global risk mapping for major diseases transmitted by Aedes aegypti and Aedes albopictus. Int J Infect Dis 67:25-35
Mei, Zhengrong; Qiu, Jianhua; Alcon, Sasha et al. (2018) Memantine improves outcomes after repetitive traumatic brain injury. Behav Brain Res 340:195-204
Bressan, Silvia; Marchetto, Luca; Lyons, Todd W et al. (2018) A Systematic Review and Meta-Analysis of the Management and Outcomes of Isolated Skull Fractures in Children. Ann Emerg Med 71:714-724.e2
Kantor, David B; Hirshberg, Eliotte L; McDonald, Molly C et al. (2018) Fluid Balance Is Associated with Clinical Outcomes and Extravascular Lung Water in Children with Acute Asthma Exacerbation. Am J Respir Crit Care Med 197:1128-1135
Sigfrid, L; Reusken, C; Eckerle, I et al. (2018) Preparing clinicians for (re-)emerging arbovirus infectious diseases in Europe. Clin Microbiol Infect 24:229-239
Michelson, Kenneth A; Hudgins, Joel D; Burke, Laura G et al. (2018) Trends in Severe Pediatric Emergency Conditions in a National Cohort, 2008 to 2014. Pediatr Emerg Care :
Thézé, Julien; Li, Tony; du Plessis, Louis et al. (2018) Genomic Epidemiology Reconstructs the Introduction and Spread of Zika Virus in Central America and Mexico. Cell Host Microbe 23:855-864.e7

Showing the most recent 10 out of 118 publications