This application seeks to renew an Institutional Research Training Grant that supports fellowship training in the Department of Pediatrics at Duke University Medical Center. The long-term objective of the training program is to foster the growth and development of pediatric investigators who are prepared to pursue independent academic careers examining important issues relevant to the health and wellbeing of children. The program will exploit the rich research and training resources at Duke University, including a cadre of faculty in pediatrics and other departments who share common research interests and frequent scholarly interactions. The program will generally provide funding for two years of investigation and will emphasize the application of cell and molecular biologic approaches and rigorous clinical and epidemiologic methods to improve our understanding of the processes that underlie pediatric diseases and to develop new and effective therapies for children. Trainees will have access to sufficient space and resources and will benefit from the extensive educational activities at Duke University, including didactic coursework, journal clubs, and relevant seminars. The principal investigator and the program director will receive assistance from an internal advisory board and an external advisory board to select candidate trainees, to review the scholarly progress of trainees, and to ensure the optimal operation of the program. The collaboration of established pediatric investigators and outstanding scientists in other departments who are pursuing questions relevant to pediatrics provides a unique opportunity for the training of pediatric fellows in the application of experimental methods to childhood diseases. As such, this program should foster the development of new pediatric scholars to lead the way for future advances in child health.

Public Health Relevance

There is a paramount need for individuals knowledgeable in clinical aspects of pediatrics and skilled in modern scientific methods who will develop novel approaches to the understanding and treatment of childhood diseases and who will thereby improve child health. The proposed training program will develop talented pediatric fellows into pediatric physician-scientists who will pursue independent academic careers and meet this need.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
2T32HD043029-11A1
Application #
8473345
Study Section
Special Emphasis Panel (ZHD1-DRG-D (59))
Program Officer
Winer, Karen
Project Start
2002-07-01
Project End
2018-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
11
Fiscal Year
2013
Total Cost
$237,041
Indirect Cost
$19,250
Name
Duke University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Page, Laura C; Gastaldelli, Amalia; Gray, Sarah M et al. (2018) Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans. Diabetes 67:1976-1985
Wang, Laura A; Smith, P Brian; Laughon, Matthew et al. (2018) Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants. Early Hum Dev 125:26-30
Thompson, Elizabeth J; Greenberg, Rachel G; Kumar, Karan et al. (2018) Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. J Pediatr 199:231-236
Bensimhon, Adam R; Williams, Anna E; Gbadegesin, Rasheed A (2018) Treatment of steroid-resistant nephrotic syndrome in the genomic era. Pediatr Nephrol :
Puia-Dumitrescu, Mihai; Bretzius, Olivia M; Brown, Nia et al. (2018) Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge. J Pediatr 203:131-136
Kumar, Karan R; Clark, David A; Kim, Evan M et al. (2018) Association of Atrial Septal Defects and Bronchopulmonary Dysplasia in Premature Infants. J Pediatr 202:56-62.e2
Heath, Travis S; Greenberg, Rachel G; Hupp, Susan R et al. (2018) Effects of Methadone on Corrected Q-T Interval Prolongation in Critically Ill Children. J Pediatr Pharmacol Ther 23:119-124
Pelletier, Jonathan H; Kumar, Karan R; Engen, Rachel et al. (2018) Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings. Pediatr Nephrol 33:1773-1780
Gulack, Brian C; Greenberg, Rachel; Clark, Reese H et al. (2018) A multi-institution analysis of predictors of timing of inguinal hernia repair among premature infants. J Pediatr Surg 53:784-788
Zhang, Cecilia J; Bidlingmaier, Martin; Altaye, Mekibib et al. (2017) Acute administration of acyl, but not desacyl ghrelin, decreases blood pressure in healthy humans. Eur J Endocrinol 176:123-132

Showing the most recent 10 out of 54 publications