The objective of the Developmental Biology (DB) Training Program, for which this application is seeking support, is to provide scientific and academic training to predoctoral individuals from diverse backgrounds to pursue investigative careers and become future leaders in the biomedical sciences. The DB Training Program will be an integral but distinct part of the umbrella Weill Cornell Graduate School of Medical Sciences Program, which is jointly administered by the Weill Cornell Medical College and the Memorial Sloan-Kettering Cancer Institute. The program will be interdisciplinary and will incorporate research programs in Developmental Biology from six out of its nine Programs of Study, including Cell and Developmental Biology, Biochemistry &Structural Biology, Molecular Biology, Pharmacology, Neurosciences, and Physiology, Biophysics, and Systems Biology. The DB Training Program will include 44 faculty members from both institutions with strong collective experience in academic research and training of pre- and post-doctoral students. The research interests in the DB Training Program are represented by the following five areas: Developmental Genetics, Patterning of Tissues and Organs, Stems Cells, Signaling in Development, and Human Development and Disease. Eligible students will be selected by the program director and four Executive Committee members, based on their promise of excellence. The DB Training Program will include a core curriculum of courses and electives, three laboratory rotations, an advanced developmental biology course, as well as participation in Graduate Student Research Seminars. Eligible DB Training Program trainees will be selected for stipend and tuition support during Years 3 and 4 of training. During the training the students will be mentored by the program director, and they will attend specialized DB Training Program events, including seminars by invited speakers, Research-in-Progress seminars, and a Developmental Biology Symposium. The number of faculty and students engaged in studies in the Developmental Biology Training Program has steadily increased over the past decade, and presently includes 38 training grant-eligible students, five of whom (13%) are minority students. To provide training of students with a commitment to excellence, support is sought for a total of eight graduate students in their third and fourth year of training.

Public Health Relevance

The purpose of this NRSA application for a Developmental Biology Training Program is to recruit, train, and mentor students from diverse backgrounds who show high promise of scientific excellence. It is expected that these trainees will assume future leadership roles in the various fields of biomedical research in the United States.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Mukhopadhyay, Mahua
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Weill Medical College of Cornell University
Anatomy/Cell Biology
Schools of Medicine
New York
United States
Zip Code
Mende, Michael; Fletcher, Emily V; Belluardo, Josephine L et al. (2016) Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron 90:1189-202
Linder, Bastian; Grozhik, Anya V; Olarerin-George, Anthony O et al. (2015) Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome. Nat Methods 12:767-72
Schulman, Victoria K; Dobi, Krista C; Baylies, Mary K (2015) Morphogenesis of the somatic musculature in Drosophila melanogaster. Wiley Interdiscip Rev Dev Biol 4:313-34
Dobi, Krista C; Schulman, Victoria K; Baylies, Mary K (2015) Specification of the somatic musculature in Drosophila. Wiley Interdiscip Rev Dev Biol 4:357-75
Tyson, Jennifer A; Goldberg, Ethan M; Maroof, Asif M et al. (2015) Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells. Development 142:1267-78
Maretzky, Thorsten; Evers, Astrid; Le Gall, Sylvain et al. (2015) The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding. J Biol Chem 290:7416-25
Kao, Der-I; Lacko, Lauretta A; Ding, Bi-Sen et al. (2015) Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling. Stem Cell Reports 4:181-9
Lacko, Lauretta A; Massimiani, Micol; Sones, Jenny L et al. (2014) Novel expression of EGFL7 in placental trophoblast and endothelial cells and its implication in preeclampsia. Mech Dev 133:163-76
Schulman, Victoria K; Folker, Eric S; Rosen, Jonathan N et al. (2014) Syd/JIP3 and JNK signaling are required for myonuclear positioning and muscle function. PLoS Genet 10:e1004880
Tyson, Jennifer A; Anderson, Stewart A (2014) GABAergic interneuron transplants to study development and treat disease. Trends Neurosci 37:169-77

Showing the most recent 10 out of 22 publications