Randomized clinical trials (RCTs) continue to be the gold standard for assessing the efficacy and effectiveness of rehabilitation science interventions. Unfortunately, relatively few researchers have completed large-scale trials of rehabilitation interventions, and there are no centralized training programs that impart the wide array of skills necessary to conduct such studies. The NCMRR Research Plan specifies that postdoctoral training programs be established to produce researchers capable of performing clinical trials. The proposed training program at the University of Southern California will enable doctoral level scholars from rehabilitation-related fields to gain the expertise necessary to perform sophisticated clinical trials, including comparative effectiveness studies. Over a five year period, 10 Ph.D. level researchers will be recruited to undergo an intensive two-year training sequence which involves exposure to all phases of clinical trials research. Reflecting a strong interdisciplinary emphasis, faculty members from three program branches (occupational therapy, physical therapy, and advanced technology) will oversee a coordinated training experience that includes individualized mentorship plans, core coursework, participation in training seminars, immersion in externally funded projects, and writing of grant proposals and research publications. The training will be organized around four core themes: (1) the identification of effective interventions for children (pediatric rehabilitation);(2) protective and risk factors in adults with disabilities;(3) the rehabilitation and subsequent reintegration of people with disabilities into the community (acute and community-based rehabilitation);and (4) applications of innovative technology. Anticipated trainee outcomes include an increased capacity to independently conduct RCTs and an increase in the quantity and rigor of rehabilitation science publications. In the long term, the ability to train a cohort of young career scientists in RCT methodology will lead to an improved research base that will promote the development and testing of interventions that increase the effectiveness of rehabilitation services.

Public Health Relevance

In this project, young scientists will be trained to perform high quality experiments that test the effectiveness of interventions that are designed to help people with a disability. By promoting high quality research, this project will enable rehabilitation professionals such as physical therapists and occupational therapists to better assist people with a disability in their quest to live healthy and productive lives.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD064578-04
Application #
8658126
Study Section
Special Emphasis Panel (ZHD1-DSR-K (TD))
Program Officer
Nitkin, Ralph M
Project Start
2011-05-01
Project End
2016-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
4
Fiscal Year
2014
Total Cost
$293,671
Indirect Cost
$20,543
Name
University of Southern California
Department
Other Health Professions
Type
Schools of Dentistry
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Duker, Leah I Stein; Henwood, Benjamin F; Bluthenthal, Ricky N et al. (2017) Parents' perceptions of dental care challenges in male children with autism spectrum disorder: An initial qualitative exploration. Res Autism Spectr Disord 39:63-72
Sleight, Alix G; Duker, Leah I Stein (2016) Toward a Broader Role for Occupational Therapy in Supportive Oncology Care. Am J Occup Ther 70:7004360030p1-8
Martinez, Clarisa A; Mintz, Emily; Ecsedy, Andrea E et al. (2016) Constraining movement reveals motor capability in chronic stroke: An initial study. Clin Rehabil :
Rana, Manku; Yani, Moheb S; Asavasopon, Skulpan et al. (2015) Brain Connectivity Associated with Muscle Synergies in Humans. J Neurosci 35:14708-16
Chen, Yi-An; Chung, Yu-Chen; Proffitt, Rachel et al. (2015) Attentional Demand of a Virtual Reality-Based Reaching Task in Nondisabled Older Adults. J Mot Learn Dev 3:91-109
Chaspari, Theodora; Tsiartas, Andreas; Stein, Leah I et al. (2015) Sparse representation of electrodermal activity with knowledge-driven dictionaries. IEEE Trans Biomed Eng 62:960-71
Roll, Shawn C; Rana, Manku; Sigward, Susan M et al. (2015) Reliability of superficial male pelvic floor structural measurements using linear-array transperineal sonography. Ultrasound Med Biol 41:610-7
Cermak, Sharon A; Stein Duker, Leah I; Williams, Marian E et al. (2015) Sensory Adapted Dental Environments to Enhance Oral Care for Children with Autism Spectrum Disorders: A Randomized Controlled Pilot Study. J Autism Dev Disord 45:2876-88
Cermak, Sharon A; Stein Duker, Leah I; Williams, Marian E et al. (2015) Feasibility of a sensory-adapted dental environment for children with autism. Am J Occup Ther 69:6903220020p1-10
Proffitt, Rachel; Lange, Belinda (2015) Considerations in the efficacy and effectiveness of virtual reality interventions for stroke rehabilitation: moving the field forward. Phys Ther 95:441-8

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