This is a competitive renewal application of The Stanford Genome Training Program, which is one of the first NHGRI sponsored program established in 1995. This program has been highly successful and has supported and trained 119 graduate students and 44 postdoctoral fellows since it began;many of these have gone on to become leaders in their field. This application proposes to modestly increase its number of Trainees to 28 predoctoral fellows and 6 postdoctoral fellows from its existing level, consistent with its substantial increase in expansion of the program. There are presently 60 Participating Faculty in 15 different departments at Stanford. Research opportunities abound in broad areas of genomics and computational biology including genome characterization, medical genomics, technology development, comparative genomics, diversity and variation, development genomics, proteomics and metabolomics, gene regulation and systems biology, all with an "omics" emphasis. Organisms that are studied include yeast, flies, worms, fish, mice, and humans and other primates (chimpanzees, gorillas, and orangutans). The emphasis of the SGTP will be to continue to provide a broad interdisciplinary education to a wide range to trainees, to serve to coordinate genomic research and training activities across the entire campus, and to help disseminate genomic science by preparing Trainees for the next steps in their careers. The program contains many unique elements that prepare Trainees for genomics research and highly successful careers. In addition, the SGTP proposes to continue an active Diversity Action Plan (DAP). The DAP will continue to recruit, retain and train individuals of diverse backgrounds for careers in the genomic sciences.)

Public Health Relevance

The field of genomics is a rapidly expanding area that will impact all areas of science including medicine. The SGTP plans to train graduate students and postdoctoral fellows to not only have highly successful careers in this area, but form the next generation of leaders in this field in both academia, industry and related professions. )

National Institute of Health (NIH)
Institutional National Research Service Award (T32)
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Ethical, Legal, Social Implications Review Committee (GNOM)
Program Officer
Junkins, Heather
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Stanford University
Schools of Medicine
United States
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Figley, Matthew D; Bieri, Gregor; Kolaitis, Regina-Maria et al. (2014) Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. J Neurosci 34:8083-97
Wilson, Benjamin A; Petrov, Dmitri A; Messer, Philipp W (2014) Soft selective sweeps in complex demographic scenarios. Genetics 198:669-84
Meehan, Stephen; Walther, Guenther; Moore, Wayne et al. (2014) AutoGate: automating analysis of flow cytometry data. Immunol Res 58:218-23
Figley, Matthew D; Thomas, Anna; Gitler, Aaron D (2014) Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis. Neurobiol Aging 35:936.e1-4
Daneshjou, Roxana; Zappala, Zachary; Kukurba, Kim et al. (2014) PATH-SCAN: a reporting tool for identifying clinically actionable variants. Pac Symp Biocomput :229-40
Olofsson, Jessica; Sharp, Katherine A; Matis, Maja et al. (2014) Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity. Development 141:2866-74
Arribere, Joshua A; Bell, Ryan T; Fu, Becky X H et al. (2014) Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans. Genetics 198:837-46
Lovejoy, Alexander F; Riordan, Daniel P; Brown, Patrick O (2014) Transcriptome-wide mapping of pseudouridines: pseudouridine synthases modify specific mRNAs in S. cerevisiae. PLoS One 9:e110799
Buenrostro, Jason D; Araya, Carlos L; Chircus, Lauren M et al. (2014) Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nat Biotechnol 32:562-8
Jia, Jinping; Bosley, Allen D; Thompson, Abbey et al. (2014) CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. Cancer Res 74:2785-95

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