This application Is for a five year renewal (years 36-40) of an institutional training grant in cardiovascular disease epidemiology.
The aims of the training program are to develop creative and independent investigators who will contribute to our knowledge of cardiovascular disease, its pathogenesis, complications and prevention. Both the training program and trainees will evolve in response to the changing needs of cardiovascular epidemiology and science. The program is based in the Department of Epidemiology but benefits from close ties with other population and clinically-oriented departments at The Johns Hopkins Medical Institutions as well as several affiliated community-based research units. The 46 trainees in the past 10 years have been extremely successful;to date their CVs show a total of 773 publications including 45 book chapters;14 are currently in training with 84% of the 32 others in faculty (n=21) or NIH, CDC, Navy, PAHO, or research institute (n=6) positions. The progam developed 1 new course (total of 5), added promising junior faculty and increased minority recruitment efforts. As Dr. Coresh enters his 13th year of directing the program, we propose appointing new assistant program directors. We propose 5 post-doctoral slots (our originally approved size) and increasing the number of pre- doctoral slots from 4 to 7 to accommodate the increasing emphasis on epidemiology and prevention as well as our success in multi-disciplinary training across departments and schools, particularly in genetic epidemiology. Pre-doctoral candidates will enroll in the PhD program. Post-doctoral candidates without a previous degree in epidemiology will enroll in a 2-year thesis bearing master's degree. Trainees will participate in (1) a structured schedule of didactic course work, (2) journal club, seminar series, and a program-specific research-in-progress meeting, (3) """"""""hands-on"""""""" analysis of an existing data set and (4) thesis research project. A Program Director, 3 Assistant Directors and 18 other nationally recognized cardiovascular disease epidemiologists serve as potential Faculty Advisors for the trainees. The program will maintain a focus on excellence, multi-disciplinary collaboration, innovation and life-long learning,

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Silsbee, Lorraine M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Johns Hopkins University
Public Health & Prev Medicine
Schools of Public Health
United States
Zip Code
McKibben, Rebeccah A; Zhao, Di; Lutsey, Pamela L et al. (2016) Factors Associated With Change in 25-Hydroxyvitamin D Levels Over Longitudinal Follow-Up in the ARIC Study. J Clin Endocrinol Metab 101:33-43
Selvin, Elizabeth; Rawlings, Andreea; Lutsey, Pamela et al. (2016) Association of 1,5-Anhydroglucitol With Cardiovascular Disease and Mortality. Diabetes 65:201-8
Parrinello, Christina M; Sharrett, A Richey; Maruthur, Nisa M et al. (2016) Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia. Diabetes Care 39:589-95
Tan, Jingwen; Liu, Shuiqing; Segal, Jodi B et al. (2016) Warfarin use and stroke, bleeding and mortality risk in patients with end stage renal disease and atrial fibrillation: a systematic review and meta-analysis. BMC Nephrol 17:157
Cobb, Laura K; Godino, Job G; Selvin, Elizabeth et al. (2016) Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study. Am J Epidemiol 183:444-51
Agarwal, Sunil K; Wruck, Lisa; Quibrera, Miguel et al. (2016) Temporal Trends in Hospitalization for Acute Decompensated Heart Failure in the United States, 1998-2011. Am J Epidemiol 183:462-70
Mills, Katherine T; Chen, Jing; Yang, Wei et al. (2016) Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease. JAMA 315:2200-10
Mills, Katherine T; Bundy, Joshua D; Kelly, Tanika N et al. (2016) Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries. Circulation 134:441-50
Cobb, Laura K; McAdams-DeMarco, Mara A; Gudzune, Kimberly A et al. (2016) Changes in Body Mass Index and Obesity Risk in Married Couples Over 25 Years: The ARIC Cohort Study. Am J Epidemiol 183:435-43
Rubin, Jonathan; Matsushita, Kunihiro; Lazo, Mariana et al. (2016) Determinants of minimal elevation in high-sensitivity cardiac troponin T in the general population. Clin Biochem 49:657-62

Showing the most recent 10 out of 301 publications