This application is for a five year renewal, years 41-45, of an institutional training grant in cardiovascular disease epidemiology.
The aims of the training program are to develop creative and independent investigators who will contribute to our knowledge of cardiovascular disease, its pathogenesis, complications and prevention. Both the training program and trainees will evolve in response to the changing needs of benefits from close ties with other population and clinically-oriented departments at The Johns Hopkins cardiovascular epidemiology and science. The program is based in the Department of Epidemiology but Medical Institutions as well as several affiliated community-based research units. The 53 trainees in the past 10 years have been extremely successful; to date their CVs show a total of 907 total publications with nearly all doing research (30 in an academic setting and 11 are in government or industry) with 10 still training and only 2 not doing any research. Time to degree completion is on target (mean 4.2 for pre-docs and 2 for Masters) and productivity is high (pre-doc and post-doc average of 17.6 and 20.3; medians of 9.5 and 15 total recruitment efforts are robust and successful. Pre-doctoral candidates will enroll in the PhD program. Post- publications including 37 first author publications cited >50 times). All slots were filled and minority doctoral candidates without a previous degree in epidemiology will enroll in a 2-year thesis bearing master's series, and a program-specific research-in-progress meeting, 3) hands-on analysis of an existing data set degree. Trainees will participate in 1) a structured schedule of didactic course work, 2) journal club, seminar and 4) thesis research project. A Program Director, a co-director, 18 core, 5 junior participating, and 14 Affiliate excellence, mult-disciplinary collaboration, innovation and life-long learning. Faculty Members serve as potential support and mentors for the trainees. The program will maintain a focus on

Public Health Relevance

This grant trains future leaders in studying risk factors for developing heart disease with rigorous training in statistics and epidemiology to study strategies to improve disease prevention. The faculty and trainees emphasize innovative methods including genetic risk factors and radiological imaging of blood vessels as well as prevention research and efforts to decrease disparities in health outcomes.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007024-43
Application #
9278221
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Silsbee, Lorraine M
Project Start
1975-07-01
Project End
2020-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
43
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Mathews, Lena; Ogunmoroti, Oluseye; Nasir, Khurram et al. (2018) Psychological Factors and Their Association with Ideal Cardiovascular Health Among Women and Men. J Womens Health (Larchmt) 27:709-715
Loomis, Stephanie J; Li, Man; Maruthur, Nisa M et al. (2018) Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study. Diabetes 67:1684-1696
Rawlings, A M; Sharrett, A R; Golden, S H et al. (2018) Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study. Diabet Med 35:583-587
Selvin, Elizabeth; Warren, Bethany; He, Xintong et al. (2018) Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol. Clin Chem 64:843-850
Jung, Molly; Warren, Bethany; Grams, Morgan et al. (2018) Performance of non-traditional hyperglycemia biomarkers by chronic kidney disease status in older adults with diabetes: Results from the Atherosclerosis Risk in Communities Study. J Diabetes 10:276-285
Warren, Bethany; Lee, Alexandra K; Ballantyne, Christie M et al. (2018) Diagnostic Performance of 1,5-Anhydroglucitol Compared to 2-H Glucose in the Atherosclerosis Risk in Communities Study. Clin Chem 64:1536-1537
Loomis, Stephanie J; Klein, Alison P; Lee, Kristine E et al. (2018) Exome Array Analysis of Nuclear Lens Opacity. Ophthalmic Epidemiol 25:215-219
Lee, Alexandra K; Warren, Bethany; Lee, Clare J et al. (2018) The Association of Severe Hypoglycemia With Incident Cardiovascular Events and Mortality in Adults With Type 2 Diabetes. Diabetes Care 41:104-111
Power, Melinda C; Rawlings, Andreea; Sharrett, A Richey et al. (2018) Association of midlife lipids with 20-year cognitive change: A cohort study. Alzheimers Dement 14:167-177
Cooper, Lisa A; Purnell, Tanjala S; Showell, Nakiya N et al. (2018) Progress on Major Public Health Challenges: The Importance of Equity. Public Health Rep 133:15S-19S

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