The University of Washington Department of Biostatistics, with the collaboration of faculty from the Department of Medicine, Division of Cardiology, and the Department of Epidemiology, proposes to train biostatisticians for collaborative work in cardiovascular research. The grant would be the fourth renewal of a very successful training grant (73 percent of grantees with Ph.D. degrees compared to the Departmental average of 26 percent). The grant would support 7 predoctoral and one postdoctoral trainee. The Ph.D. training program consists of coursework in statistical theory; biostatistical. Theory and applications, biology electives (normal human physiology is suggested for trainees), and consulting experience. First and second year theory and a second year applied preliminary examinations must be passed at the Ph.D. level; a programming requirement must be satisfied; and a doctoral thesis must be completed. A biology oral examination is to be- satisfied in a cardiovascular area. Students are enrolled from mathematical, statistical and biological majors; entry criteria include two years of calculus, linear algebra and probability. Although prospective students with biology majors may be admitted provisionally if they have not satisfied all of the mathematical requirements. Many of the trainees in addition -to training grant support spend time as research assistants on one of the ongoing research projects of the department faculty including the Cardiovascular Health Study Morbidity and Mortality Follow-up: Coordinating Center (CHS), Antiarrhythmics versus Implantable Defibrillators (AVID), Early Access to Defibrillation for Victims Cardiac Arrest (OHH CA) (PAD), and the Multi-Ethnic Study of Atherosclerosis (MESA).

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007183-28
Application #
6627327
Study Section
Special Emphasis Panel (ZHL1-CSR-M (F1))
Program Officer
Silsbee, Lorraine M
Project Start
1976-07-01
Project End
2006-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
28
Fiscal Year
2003
Total Cost
$217,536
Indirect Cost
Name
University of Washington
Department
Biostatistics & Other Math Sci
Type
Schools of Public Health
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Shoben, Abigail B; Rudser, Kyle D; Emerson, Scott S (2017) More data, less information? Potential for nonmonotonic information growth using GEE. J Biopharm Stat 27:135-147
Sitlani, Colleen M; Heagerty, Patrick J (2014) Analyzing longitudinal data to characterize the accuracy of markers used to select treatment. Stat Med 33:2881-96
Sitlani, Colleen M; Heagerty, Patrick J; Blood, Emily A et al. (2012) Longitudinal structural mixed models for the analysis of surgical trials with noncompliance. Stat Med 31:1738-60
Voorman, Arend; Rice, Ken; Lumley, Thomas (2012) Fast computation for genome-wide association studies using boosted one-step statistics. Bioinformatics 28:1818-22
Voorman, Arend; Lumley, Thomas; McKnight, Barbara et al. (2011) Behavior of QQ-plots and genomic control in studies of gene-environment interaction. PLoS One 6:e19416
Sitlani, Colleen M; McKnight, Barbara (2011) Relative efficiency of trend tests with misspecified genetic models in stratified analyses of case-control or cohort data. Hum Hered 71:246-55
Wondergem, Robert; Graves, Bridget M; Ozment-Skelton, Tammy R et al. (2010) Lipopolysaccharides directly decrease Ca2+ oscillations and the hyperpolarization-activated nonselective cation current If in immortalized HL-1 cardiomyocytes. Am J Physiol Cell Physiol 299:C665-71
Everson-Stewart, Siobhan; Emerson, Scott S (2010) Bio-creep in non-inferiority clinical trials. Stat Med 29:2769-80
O'Brien, Jennifer J; Nathanson, Neil M (2007) Retrograde activation of STAT3 by leukemia inhibitory factor in sympathetic neurons. J Neurochem 103:288-302
Dodd, Lori E; Pepe, Margaret S (2003) Partial AUC estimation and regression. Biometrics 59:614-23

Showing the most recent 10 out of 16 publications