The purpose of the training program is to provide systematic multidisciplinary predoctoral and postdoctoral research training into the biobehavioral and psychosocial factors involved in the pathogenesis and treatment of cardiovascular diseases as well as the prevention of such diseases in high risk populations. Research training is also offered for study of neural, hormonal and immunological mechanisms that may link biobehavioral variables to cardiovascular pathology. Training is closely coordinated with several extramurally funded NIH NHLBI grants including a program project, "Biobehavioral Bases of CHD Risk and Management," a large multi-center longitudinal epidemiological study, "Hispanic Community Health Study/Study of Latinos (HCHS/SOL)" and multiple RO1 grants. The program project consists of integrated, multidisciplinary projects examining the clinical and/or preclinical markers of CHD risk associated with type 2 diabetes (Project 1), metabolic syndrome (Project 2) or hyperlipidemia (Project 3) and their involvement in the progression or amelioration of atherosclerotic CHD processes. In each project we examine modification of risk factors through interventions such as dietary restriction, exercise, stress management and/or manipulation of social environment. Outcome variables include measures of glycemic control/insulin resistance and/or dyslipidemia, oxidative stress, inflammation and overt manifestations of disease. Projects 1 and 2 recruit patients from a large community health center serving low income Blacks and Hispanics/Latinos and Project 3 examines Watanabe heritable hyperlipidemic rabbits and knockout mice. In the HCHS/SOL study the Miami field center is conducting physical exams and interviews as well as follow- ups of 4000 Cuban, South and Central Americans drawn from 24 census tracts to assess health, health risks and practices. Trainees will include 5 predoctoral and 2 postdoctoral fellows who are expected to spend at least two years in the program. Although emphasis at both the pre- and post-doctoral level is upon research, available didactic training includes multiple courses in advanced statistics as well as epidemiology, behavioral medicine, mechanisms of disease, neuroscience and molecular biology. Trainees usually undergo rotations through our program project cores in Biochemistry and Metabolism, Cardiovascular Measurement, and Data Management and Statistics. All trainees receive individual mentoring and participate in relevant program project and other research meetings.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007426-34
Application #
8293162
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Kaufmann, Peter G
Project Start
1994-07-01
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
34
Fiscal Year
2012
Total Cost
$354,473
Indirect Cost
$19,665
Name
University of Miami Coral Gables
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
625174149
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Alegria, Margarita; Molina, Kristine M; Chen, Chih-Nan (2014) Neighborhood characteristics and differential risk for depressive and anxiety disorders across racial/ethnic groups in the United States. Depress Anxiety 31:27-37
Molina, Kristine M; Simon, Yenisleidy (2014) Everyday discrimination and chronic health conditions among Latinos: the moderating role of socioeconomic position. J Behav Med 37:868-80
Birnbaum-Weitzman, O; Goldberg, R; Hurwitz, B E et al. (2014) Depressive symptoms linked to 1-h plasma glucose concentrations during the oral glucose tolerance test in men and women with the metabolic syndrome. Diabet Med 31:630-6
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Molina, Kristine M; Alcantara, Carmela (2013) Household structure, family ties, and psychological distress among U.S.-born and immigrant Latino women. J Fam Psychol 27:147-58
Molina, Kristine M; Alegria, Margarita; Mahalingam, Ramaswami (2013) A multiple-group path analysis of the role of everyday discrimination on self-rated physical health among Latina/os in the USA. Ann Behav Med 45:33-44
Saab, Patrice G; Fitzpatrick, Stephanie; Lai, Betty et al. (2011) Elevated body mass index and obesity among ethnically diverse adolescents. Ethn Dis 21:176-82
Stanziano, Damian C; Butler-Ajibade, Phoebe (2011) Differences in health-related behaviors and body mass index risk categories in African American women in college. J Natl Med Assoc 103:4-8
Farrell, Kristen; Antoni, Michael H (2010) Insulin resistance, obesity, inflammation, and depression in polycystic ovary syndrome: biobehavioral mechanisms and interventions. Fertil Steril 94:1565-74
Hurwitz, Barry E; Coryell, Virginia T; Parker, Meela et al. (2010) Chronic fatigue syndrome: illness severity, sedentary lifestyle, blood volume and evidence of diminished cardiac function. Clin Sci (Lond) 118:125-35

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